Product Information
Molecular Weight(Da):23449Da
Protein NameFAD-linked sulfhydryl oxidase ALR
Human Gene Id2671
Human Swiss Prot NoP55789
Mouse Gene Id11692
Mouse Swiss Prot NoP56213
Rat Gene Id27100
Rat Swiss Prot NoQ63042
SpecificityALR Polyclonal Antibody detects endogenous levels of ALR protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameGFER; ALR; HERV1; HPO; FAD-linked sulfhydryl oxidase ALR; Augmenter of liver regeneration; hERV1; Hepatopoietin
Observed Band(KD)24
Functioncatalytic activity:4 R'C(R)SH + O(2) = 2 R'C(R)S-S(R)CR' + 2 H(2)O.,cofactor:FAD.,function:FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation.,similarity:Contains 1 ERV/ALR sulfhydryl oxidase domain.,subunit:Homodimer.,
Subcellular Locationextracellular region,cytoplasm,mitochondrion,mitochondrial intermembrane space,
ExpressionFetal liver,Liver,Placenta,Renal cyst lining cell,Skin,
Backgroundgrowth factor, augmenter of liver regeneration(GFER) Homo sapiens The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008],