World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
Glut4 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight54787Da
Protein NameSolute carrier family 2 facilitated glucose transporter member 4
Human Gene Id6517
Human Swiss Prot NoP14672
Mouse Gene Id20528
Mouse Swiss Prot NoP14142
Rat Gene Id25139
Rat Swiss Prot NoP19357
SpecificityGlut4 Polyclonal Antibody detects endogenous levels of Glut4 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSLC2A4; GLUT4; Solute carrier family 2, facilitated glucose transporter member 4; Glucose transporter type 4, insulin-responsive; GLUT-4
Observed Band(KD)56
Functiondisease:Defects in SLC2A4 may be a cause of noninsulin-dependent diabetes mellitus (NIDDM) [MIM:125853]. Defects in SLC2A4 may be a cause of certain post-receptor defects in NIDDM. The variant in position Ile-383 is found in a small number of NIDDM patients, but seems not to be found in nondiabetic subjects.,function:Insulin-regulated facilitative glucose transporter.,miscellaneous:Insulin-stimulated phosphorylation of TBC1D4 is required for GLUT4 translocation.,online information:GLUT4 entry,PTM:Sumoylated.,similarity:Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.,subcellular location:Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration.,subunit:Binds to DAX
Subcellular Locationmultivesicular body,cytosol,plasma membrane,integral component of plasma membrane,clathrin-coated pit,external side of plasma membrane,endomembrane system,vesicle membrane,membrane,integral component of membrane,clathrin-co
ExpressionColon,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human SLC2A4. AA range:21-70
Gene NameSLC2A4
DilutionWB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300
Backgroundsolute carrier family 2 member 4(SLC2A4) Homo sapiens This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75523-Conjugate. Price: $485 / Size: 100μl.
E20-75523-FITC$485 / 100μlE20-75523-Biotin$485 / 100μlE20-75523-HRP$485 / 100μlE20-75523-AP$485 / 100μlE20-75523-AF350$485 / 100μlE20-75523-AF405M$485 / 100μlE20-75523-AF488$485 / 100μlE20-75523-AF514$485 / 100μlE20-75523-AF532$485 / 100μlE20-75523-AF555$485 / 100μlE20-75523-AF568$485 / 100μlE20-75523-AF405S$485 / 100μlE20-75523-AF405L$485 / 100μlE20-75523-AF546$485 / 100μlE20-75523-AF594$485 / 100μlE20-75523-AF610$485 / 100μlE20-75523-AF635$485 / 100μlE20-75523-AF647$485 / 100μlE20-75523-AF680$485 / 100μlE20-75523-AF700$485 / 100μlE20-75523-AF750$485 / 100μlE20-75523-AF790$485 / 100μlE20-75523-APC$485 / 100μlE20-75523-PE$485 / 100μlE20-75523-Cy3$485 / 100μlE20-75523-Cy5$485 / 100μlE20-75523-Cy5.5$485 / 100μlE20-75523-Cy7$485 / 100μlE20-75523-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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