TRPC3 Polyclonal Antibody

Name: TRPC3 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75520
Price: 225 USD
Availability: InStock

E20-75520Cite ID: EN0055653Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight96009Da

Protein NameShort transient receptor potential channel 3

Human Gene Id7222

Human Swiss Prot NoQ13507

Mouse Swiss Prot NoQ9QZC1

Rat Swiss Prot NoQ9JMI9

SpecificityTRPC3 Polyclonal Antibody detects endogenous levels of TRPC3 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameTRPC3; TRP3; Short transient receptor potential channel 3; TrpC3; Transient receptor protein 3; TRP-3; hTrp-3; hTrp3

Observed Band(KD)97

Functionfunction:Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.,similarity:Belongs to the transient receptor family. STrpC subfamily.,similarity:Contains 5 ANK repeats.,subunit:Interacts with TRPC1. Interacts with ITPR3. Interacts with MX1 and RNF24.,tissue specificity:Expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis.,

Subcellular Locationplasma membrane,integral component of plasma membrane,integral component of membrane,

ExpressionBrain,Embryonic kidney,Fetal brain,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human TRPC3. AA range:411-460

Gene NameTRPC3

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/20000. Not yet tested in other applications.

Backgroundtransient receptor potential cation channel subfamily C member 3(TRPC3) Homo sapiens The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75520-Conjugate. Price: $485 / Size: 100μl.

E20-75520-FITC$485 / 100μlE20-75520-Biotin$485 / 100μlE20-75520-HRP$485 / 100μlE20-75520-AP$485 / 100μlE20-75520-AF350$485 / 100μlE20-75520-AF405M$485 / 100μlE20-75520-AF488$485 / 100μlE20-75520-AF514$485 / 100μlE20-75520-AF532$485 / 100μlE20-75520-AF555$485 / 100μlE20-75520-AF568$485 / 100μlE20-75520-AF405S$485 / 100μlE20-75520-AF405L$485 / 100μlE20-75520-AF546$485 / 100μlE20-75520-AF594$485 / 100μlE20-75520-AF610$485 / 100μlE20-75520-AF635$485 / 100μlE20-75520-AF647$485 / 100μlE20-75520-AF680$485 / 100μlE20-75520-AF700$485 / 100μlE20-75520-AF750$485 / 100μlE20-75520-AF790$485 / 100μlE20-75520-APC$485 / 100μlE20-75520-PE$485 / 100μlE20-75520-Cy3$485 / 100μlE20-75520-Cy5$485 / 100μlE20-75520-Cy5.5$485 / 100μlE20-75520-Cy7$485 / 100μlE20-75520-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.