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Cell Signal Transduction Research Antibodies
CD47 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight35214Da
Protein NameLeukocyte surface antigen CD47
Human Gene Id961
Human Swiss Prot NoQ08722
Mouse Swiss Prot NoQ61735
SpecificityCD47 Polyclonal Antibody detects endogenous levels of CD47 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD47; MER6; Leukocyte surface antigen CD47; Antigenic surface determinant protein OA3; Integrin-associated protein; IAP; Protein MER6; CD47
Observed Band(KD)35
Functionfunction:Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with THBS1 and fibrinogen (By similarity). Monomer. Inter
Subcellular Locationplasma membrane,integral component of plasma membrane,integral component of membrane,extracellular exosome,
ExpressionErythrocyte,Hippocampus,Leiomyosarcoma,Liver,Myelomonocyte,Ovarian adenocarcinoma,Ovary,T-c
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD47. AA range:61-110
Gene NameCD47
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
BackgroundCD47 molecule(CD47) Homo sapiens This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010],
Conjugated Antibody
This product is also available conjugated. Format: E20-75509-Conjugate. Price: $485 / Size: 100μl.
E20-75509-FITC$485 / 100μlE20-75509-Biotin$485 / 100μlE20-75509-HRP$485 / 100μlE20-75509-AP$485 / 100μlE20-75509-AF350$485 / 100μlE20-75509-AF405M$485 / 100μlE20-75509-AF488$485 / 100μlE20-75509-AF514$485 / 100μlE20-75509-AF532$485 / 100μlE20-75509-AF555$485 / 100μlE20-75509-AF568$485 / 100μlE20-75509-AF405S$485 / 100μlE20-75509-AF405L$485 / 100μlE20-75509-AF546$485 / 100μlE20-75509-AF594$485 / 100μlE20-75509-AF610$485 / 100μlE20-75509-AF635$485 / 100μlE20-75509-AF647$485 / 100μlE20-75509-AF680$485 / 100μlE20-75509-AF700$485 / 100μlE20-75509-AF750$485 / 100μlE20-75509-AF790$485 / 100μlE20-75509-APC$485 / 100μlE20-75509-PE$485 / 100μlE20-75509-Cy3$485 / 100μlE20-75509-Cy5$485 / 100μlE20-75509-Cy5.5$485 / 100μlE20-75509-Cy7$485 / 100μlE20-75509-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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