Histone H3 Polyclonal Antibody

Name: Histone H3 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75499
Price: 225 USD
Availability: InStock

E20-75499Cite ID: EN0055632Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight15404/15388/15328/15214Da

Protein NameHistone H3.1/Histone H3.2/Histone H3.3/Histone H3.3C

Human Gene Id8350/8351/8352/8353/8354/8355/8356/8357/8358/8968/126961/333932/653604/3020/3021/440093

Human Swiss Prot NoP68431/Q71DI3/P84243/Q6NXT2

Mouse Gene Id319152/15077/15078/625328

Rat Gene Id291159/100361558

Rat Swiss Prot NoQ6LED0/P84245

SpecificityHistone H3 Polyclonal Antibody detects endogenous levels of Histone H3 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameHIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3; H3F3C; Histone H3.3C; Histone H3.5

Observed Band(KD)17

Functioncaution:Was originally (PubMed:2587222) thought to originate from mouse.,developmental stage:Expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation.,function:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.,mass spectrometry:Monoisotopic with N-acetylserine PubMed:16457589,miscellaneous:This histone is only present in mammals and is enriched in acetylation of Lys-15 and dimethylation of Lys-10 (H3K9me2).,PTM:Acetylation is generally l

Subcellular Locationnuclear chromosome,nuclear chromosome, telomeric region,nucleosome,nuclear nucleosome,extracellular region,nucleus,nucleoplasm,cell-cell adherens junction,membrane,protein complex,extracellular exosome,

ExpressionBlood,Epithelium,Kidney,Lung,Ovary,Spleen,Uterus,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenSynthesized peptide derived from the Internal region of human Histone H3.

Gene NameHIST1H3A/HIST1H3/HIST1H3C/HIST1H3D/HIST1H3E/HIST1H3F/HIST1H3G/HIST1H3H/HIST1H3I/HIST1H3J/HIST2H3A/HIST2H3C/HIST2H3D/H3F3A/H3F3B/H3F3C

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Backgroundhistone cluster 1 H3 family member a(HIST1H3A) Homo sapiens Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75499-Conjugate. Price: $485 / Size: 100μl.

E20-75499-FITC$485 / 100μlE20-75499-Biotin$485 / 100μlE20-75499-HRP$485 / 100μlE20-75499-AP$485 / 100μlE20-75499-AF350$485 / 100μlE20-75499-AF405M$485 / 100μlE20-75499-AF488$485 / 100μlE20-75499-AF514$485 / 100μlE20-75499-AF532$485 / 100μlE20-75499-AF555$485 / 100μlE20-75499-AF568$485 / 100μlE20-75499-AF405S$485 / 100μlE20-75499-AF405L$485 / 100μlE20-75499-AF546$485 / 100μlE20-75499-AF594$485 / 100μlE20-75499-AF610$485 / 100μlE20-75499-AF635$485 / 100μlE20-75499-AF647$485 / 100μlE20-75499-AF680$485 / 100μlE20-75499-AF700$485 / 100μlE20-75499-AF750$485 / 100μlE20-75499-AF790$485 / 100μlE20-75499-APC$485 / 100μlE20-75499-PE$485 / 100μlE20-75499-Cy3$485 / 100μlE20-75499-Cy5$485 / 100μlE20-75499-Cy5.5$485 / 100μlE20-75499-Cy7$485 / 100μlE20-75499-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.