World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
SRY Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight23884Da
Protein NameSex-determining region Y protein
Human Gene Id6736
Human Swiss Prot NoQ05066
Mouse Swiss Prot NoQ05738
SpecificitySRY Polyclonal Antibody detects endogenous levels of SRY protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSRY; TDF; Sex-determining region Y protein; Testis-determining factor
Observed Band(KD)25
Functiondisease:Defects in SRY are a cause of gonadal dysgenesis XY female type (GDXY) [MIM:306100]; also known as 'XY females' or Swyer syndrome. Patients are found to have a 46,XY karyotype. They suffer rapid and early degeneration of their gonads, which are present in the adult as 'streak gonads', consisting mainly of fibrous tissue and variable amounts of ovarian stroma. As a result these patients do not develop secondary sexual characteristics at puberty. The external genitalia in these subjects are completely female, and Muellerian structures are normal. In contrast, subjects with 46,XY partial gonadal dysgenesis have ambiguous genitalia, a mix of Muellerian and Wolffian structures, and dysgenic gonads.,disease:Defects in SRY are a cause of true hermaphroditism [MIM:235600]. A true hermaphrodite must have both mature ovarian and mature testicular tissue with histologic evidence of follicle
Subcellular Locationnucleus,nucleoplasm,cytoplasm,nuclear speck,
ExpressionBlood,Sperm,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the Internal region of human SRY.
Gene NameSRY
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgroundsex determining region Y(SRY) Homo sapiens This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75497-Conjugate. Price: $485 / Size: 100μl.
E20-75497-FITC$485 / 100μlE20-75497-Biotin$485 / 100μlE20-75497-HRP$485 / 100μlE20-75497-AP$485 / 100μlE20-75497-AF350$485 / 100μlE20-75497-AF405M$485 / 100μlE20-75497-AF488$485 / 100μlE20-75497-AF514$485 / 100μlE20-75497-AF532$485 / 100μlE20-75497-AF555$485 / 100μlE20-75497-AF568$485 / 100μlE20-75497-AF405S$485 / 100μlE20-75497-AF405L$485 / 100μlE20-75497-AF546$485 / 100μlE20-75497-AF594$485 / 100μlE20-75497-AF610$485 / 100μlE20-75497-AF635$485 / 100μlE20-75497-AF647$485 / 100μlE20-75497-AF680$485 / 100μlE20-75497-AF700$485 / 100μlE20-75497-AF750$485 / 100μlE20-75497-AF790$485 / 100μlE20-75497-APC$485 / 100μlE20-75497-PE$485 / 100μlE20-75497-Cy3$485 / 100μlE20-75497-Cy5$485 / 100μlE20-75497-Cy5.5$485 / 100μlE20-75497-Cy7$485 / 100μlE20-75497-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits