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Cell Signal Transduction Research Antibodies
HMG-1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight24894Da
Protein NameHigh mobility group protein B1
Human Gene Id3146
Human Swiss Prot NoP09429
Mouse Gene Id100862258
Mouse Swiss Prot NoP63158
Rat Gene Id25459
Rat Swiss Prot NoP63159
SpecificityHMG-1 Polyclonal Antibody detects endogenous levels of HMG-1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameHMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
Observed Band(KD)25
Functionfunction:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains.,
Subcellular Locationcondensed chromosome,extracellular region,extracellular space,nucleus,nucleoplasm,endosome,early endosome,endoplasmic reticulum-Golgi intermediate compartment,plasma membrane,cell surface,transcriptional repressor complex,
ExpressionBrain,Cerebellum,Cervix,Epithelium,Mammary carcinoma,Myeloblast cell line,S
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the N-terminal region of human HMG-1.
Gene NameHMGB1
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgroundhigh mobility group box 1(HMGB1) Homo sapiens This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015],
Conjugated Antibody
This product is also available conjugated. Format: E20-75496-Conjugate. Price: $485 / Size: 100μl.
E20-75496-FITC$485 / 100μlE20-75496-Biotin$485 / 100μlE20-75496-HRP$485 / 100μlE20-75496-AP$485 / 100μlE20-75496-AF350$485 / 100μlE20-75496-AF405M$485 / 100μlE20-75496-AF488$485 / 100μlE20-75496-AF514$485 / 100μlE20-75496-AF532$485 / 100μlE20-75496-AF555$485 / 100μlE20-75496-AF568$485 / 100μlE20-75496-AF405S$485 / 100μlE20-75496-AF405L$485 / 100μlE20-75496-AF546$485 / 100μlE20-75496-AF594$485 / 100μlE20-75496-AF610$485 / 100μlE20-75496-AF635$485 / 100μlE20-75496-AF647$485 / 100μlE20-75496-AF680$485 / 100μlE20-75496-AF700$485 / 100μlE20-75496-AF750$485 / 100μlE20-75496-AF790$485 / 100μlE20-75496-APC$485 / 100μlE20-75496-PE$485 / 100μlE20-75496-Cy3$485 / 100μlE20-75496-Cy5$485 / 100μlE20-75496-Cy5.5$485 / 100μlE20-75496-Cy7$485 / 100μlE20-75496-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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