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Cell Signal Transduction Research Antibodies
SAMHD1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight72201Da
Protein NameSAM domain and HD domain-containing protein 1
Human Gene Id25939
Human Swiss Prot NoQ9Y3Z3
Mouse Gene Id56045
Mouse Swiss Prot NoQ60710
SpecificitySAMHD1 Polyclonal Antibody detects endogenous levels of SAMHD1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSAMHD1; MOP5; SAM domain and HD domain-containing protein 1; Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5
Observed Band(KD)72
Functionfunction:May play a role in mediating proinflammatory responses to TNF-alpha signaling.,induction:By interferon gamma. Up-regulated in TNF-alpha treated lung fibroblasts.,similarity:Contains 1 HD domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,tissue specificity:Expressed in heart, skeletal muscle, spleen, liver, small intestine, placenta, lung and peripheral blood leukocytes. No expression is seen in brain and thymus.,
Subcellular LocationNucleus . Chromosome . Localizes to sites of DNA double-strand breaks in response to DNA damage. .
ExpressionExpressed in heart, skeletal muscle, spleen, liver, small intestine, placenta, lung and peripheral blood leukocytes (PubMed:11064105). No expression is seen in brain and thymus (PubMed:11064105).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human SAMHD1. AA range:431-480
Gene NameSAMHD1
DilutionWestern Blot:1/500 - 1/2000. IHC-p:1/100-1/300. ELISA:1/20000. Not yet tested in other applications.
BackgroundSAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1(SAMHD1) Homo sapiens This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010],
Conjugated Antibody
This product is also available conjugated. Format: E20-75491-Conjugate. Price: $485 / Size: 100μl.
E20-75491-FITC$485 / 100μlE20-75491-Biotin$485 / 100μlE20-75491-HRP$485 / 100μlE20-75491-AP$485 / 100μlE20-75491-AF350$485 / 100μlE20-75491-AF405M$485 / 100μlE20-75491-AF488$485 / 100μlE20-75491-AF514$485 / 100μlE20-75491-AF532$485 / 100μlE20-75491-AF555$485 / 100μlE20-75491-AF568$485 / 100μlE20-75491-AF405S$485 / 100μlE20-75491-AF405L$485 / 100μlE20-75491-AF546$485 / 100μlE20-75491-AF594$485 / 100μlE20-75491-AF610$485 / 100μlE20-75491-AF635$485 / 100μlE20-75491-AF647$485 / 100μlE20-75491-AF680$485 / 100μlE20-75491-AF700$485 / 100μlE20-75491-AF750$485 / 100μlE20-75491-AF790$485 / 100μlE20-75491-APC$485 / 100μlE20-75491-PE$485 / 100μlE20-75491-Cy3$485 / 100μlE20-75491-Cy5$485 / 100μlE20-75491-Cy5.5$485 / 100μlE20-75491-Cy7$485 / 100μlE20-75491-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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