World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
DcR1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight27395Da
Protein NameTumor necrosis factor receptor superfamily member 10C
Human Gene Id8794
Human Swiss Prot NoO14798
SpecificityDcR1 Polyclonal Antibody detects endogenous levels of DcR1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTNFRSF10C; DCR1; LIT; TRAILR3; TRID; Tumor necrosis factor receptor superfamily member 10C; Antagonist decoy receptor for TRAIL/Apo-2L; Decoy TRAIL receptor without death domainDecoy receptor 1; DcR1; Lymphocyte inhibitor of TRAIL; TNF-related apoptosis-inducing ligand receptor 3; TRAIL receptor 3; TRAIL-R3; TRAIL receptor without an intracellular domain; CD263
Observed Band(KD)27
Functionfunction:Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.,PTM:N-glycosylated and O-glycosylated.,similarity:Contains 3 TNFR-Cys repeats.,tissue specificity:Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.,
Subcellular LocationCell membrane; Lipid-anchor, GPI-anchor.
ExpressionHigher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human TNFRSF10C. AA range:11-60
Gene NameTNFRSF10C
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundTNF receptor superfamily member 10c(TNFRSF10C) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75483-Conjugate. Price: $485 / Size: 100μl.
E20-75483-FITC$485 / 100μlE20-75483-Biotin$485 / 100μlE20-75483-HRP$485 / 100μlE20-75483-AP$485 / 100μlE20-75483-AF350$485 / 100μlE20-75483-AF405M$485 / 100μlE20-75483-AF488$485 / 100μlE20-75483-AF514$485 / 100μlE20-75483-AF532$485 / 100μlE20-75483-AF555$485 / 100μlE20-75483-AF568$485 / 100μlE20-75483-AF405S$485 / 100μlE20-75483-AF405L$485 / 100μlE20-75483-AF546$485 / 100μlE20-75483-AF594$485 / 100μlE20-75483-AF610$485 / 100μlE20-75483-AF635$485 / 100μlE20-75483-AF647$485 / 100μlE20-75483-AF680$485 / 100μlE20-75483-AF700$485 / 100μlE20-75483-AF750$485 / 100μlE20-75483-AF790$485 / 100μlE20-75483-APC$485 / 100μlE20-75483-PE$485 / 100μlE20-75483-Cy3$485 / 100μlE20-75483-Cy5$485 / 100μlE20-75483-Cy5.5$485 / 100μlE20-75483-Cy7$485 / 100μlE20-75483-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits