World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
CD223 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight57437Da
Protein NameLymphocyte activation gene 3 protein
Human Gene Id3902
Human Swiss Prot NoP18627
Mouse Gene Id16768
Mouse Swiss Prot NoQ61790
Rat Gene Id297596
Rat Swiss Prot NoQ5BK54
SpecificityCD223 Polyclonal Antibody detects endogenous levels of CD223 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameLAG3; FDC; Lymphocyte activation gene 3 protein; LAG-3; Protein FDC; CD223
Observed Band(KD)57
Functionfunction:Involved in lymphocyte activation. Binds to HLA class-II antigens.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:On cell surface of activated NK and T-lymphocytes.,
Subcellular Location[Lymphocyte activation gene 3 protein]: Cell membrane ; Single-pass type I membrane protein .; [Secreted lymphocyte activation gene 3 protein]: Secreted . Produced following cleavage of the main chain. .
ExpressionPrimarily expressed in activated T-cells and a subset of natural killer (NK) cells.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human LAG3. AA range:91-140
Gene NameLAG3
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundlymphocyte activating 3(LAG3) Homo sapiens Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75480-Conjugate. Price: $485 / Size: 100μl.
E20-75480-FITC$485 / 100μlE20-75480-Biotin$485 / 100μlE20-75480-HRP$485 / 100μlE20-75480-AP$485 / 100μlE20-75480-AF350$485 / 100μlE20-75480-AF405M$485 / 100μlE20-75480-AF488$485 / 100μlE20-75480-AF514$485 / 100μlE20-75480-AF532$485 / 100μlE20-75480-AF555$485 / 100μlE20-75480-AF568$485 / 100μlE20-75480-AF405S$485 / 100μlE20-75480-AF405L$485 / 100μlE20-75480-AF546$485 / 100μlE20-75480-AF594$485 / 100μlE20-75480-AF610$485 / 100μlE20-75480-AF635$485 / 100μlE20-75480-AF647$485 / 100μlE20-75480-AF680$485 / 100μlE20-75480-AF700$485 / 100μlE20-75480-AF750$485 / 100μlE20-75480-AF790$485 / 100μlE20-75480-APC$485 / 100μlE20-75480-PE$485 / 100μlE20-75480-Cy3$485 / 100μlE20-75480-Cy5$485 / 100μlE20-75480-Cy5.5$485 / 100μlE20-75480-Cy7$485 / 100μlE20-75480-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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