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Cell Signal Transduction Research Antibodies
BST-1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight35724Da
Protein NameADP-ribosyl cyclase 2
Human Gene Id683
Human Swiss Prot NoQ10588
Mouse Gene Id12182
Mouse Swiss Prot NoQ64277
Rat Gene Id81506
Rat Swiss Prot NoQ63072
SpecificityBST-1 Polyclonal Antibody detects endogenous levels of BST-1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameBST1; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD157
Observed Band(KD)36
Functioncatalytic activity:NAD(+) + H(2)O = ADP-ribose + nicotinamide.,disease:Rheumatoid arthritis (RA) patients show enhanced expression of BST-1 transcripts in bone marrow stromal cell lines. This suggests that BST-1 overexpression may play a role in B-cell abnormalities in RA.,function:Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.,similarity:Belongs to the ADP-ribosyl cyclase family.,subunit:Homodimer.,tissue specificity:Widely expressed.,
Subcellular LocationCell membrane; Lipid-anchor, GPI-anchor.
ExpressionWidely expressed.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from ADP-ribosyl cyclase 2 at AA range: 211-260
Gene NameBST1
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundbone marrow stromal cell antigen 1(BST1) Homo sapiens Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75476-Conjugate. Price: $485 / Size: 100μl.
E20-75476-FITC$485 / 100μlE20-75476-Biotin$485 / 100μlE20-75476-HRP$485 / 100μlE20-75476-AP$485 / 100μlE20-75476-AF350$485 / 100μlE20-75476-AF405M$485 / 100μlE20-75476-AF488$485 / 100μlE20-75476-AF514$485 / 100μlE20-75476-AF532$485 / 100μlE20-75476-AF555$485 / 100μlE20-75476-AF568$485 / 100μlE20-75476-AF405S$485 / 100μlE20-75476-AF405L$485 / 100μlE20-75476-AF546$485 / 100μlE20-75476-AF594$485 / 100μlE20-75476-AF610$485 / 100μlE20-75476-AF635$485 / 100μlE20-75476-AF647$485 / 100μlE20-75476-AF680$485 / 100μlE20-75476-AF700$485 / 100μlE20-75476-AF750$485 / 100μlE20-75476-AF790$485 / 100μlE20-75476-APC$485 / 100μlE20-75476-PE$485 / 100μlE20-75476-Cy3$485 / 100μlE20-75476-Cy5$485 / 100μlE20-75476-Cy5.5$485 / 100μlE20-75476-Cy7$485 / 100μlE20-75476-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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