EMMPRIN Polyclonal Antibody

Name: EMMPRIN Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75471
Price: 225 USD
Availability: InStock

E20-75471Cite ID: EN0055604Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight42200Da

Protein NameBasigin

Human Gene Id682

Human Swiss Prot NoP35613

Mouse Swiss Prot NoP18572

SpecificityEMMPRIN Polyclonal Antibody detects endogenous levels of EMMPRIN protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameBSG; Basigin; 5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD147

Observed Band(KD)42

Functionfunction:Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.,induction:Enriched on the surface of tumor cells. Up-regulated in gliomas. Its expression levels correlate with malignant potential of the tumor.,online information:Blood group antigen gene mutation database,PTM:N-glycosylated.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subcellular location:Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spec

Subcellular LocationMelanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .; [Isoform 1]: Cell membrane ; Single-pass type I membrane protein . Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment .; [Isoform 2]: Cell membrane ; Single-pass type I membrane protein . Endosome . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Basolateral cell membrane ; Single-pass type I membrane protein .; [Isoform 3]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 4]: Cell membrane ; Single-pass type I membrane protein .

Expression[Isoform 1]: Retina-specific (PubMed:25957687). Expressed in retinal cone photoreceptors (at protein level) (PubMed:25957687). ; [Isoform 2]: Expressed in erythrocytes (at protein level) (PubMed:26195724, PubMed:28409866). Highly expressed in melanoma cell lines (at protein level) (PubMed:11992541). Highly expressed in the heart, kidney, skeletal muscle and testis (PubMed:21536654). ; [Isoform 3]: Highly expressed in the bone marrow, fetal liver, lung, testis and thymus. ; [Isoform 4]: Highly expressed in the bone marrow, fetal liver, lung, testis and thymus.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human BSG. AA range:221-270

Gene NameBSG

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Backgroundbasigin (Ok blood group)(BSG) Homo sapiens The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75471-Conjugate. Price: $485 / Size: 100μl.

E20-75471-FITC$485 / 100μlE20-75471-Biotin$485 / 100μlE20-75471-HRP$485 / 100μlE20-75471-AP$485 / 100μlE20-75471-AF350$485 / 100μlE20-75471-AF405M$485 / 100μlE20-75471-AF488$485 / 100μlE20-75471-AF514$485 / 100μlE20-75471-AF532$485 / 100μlE20-75471-AF555$485 / 100μlE20-75471-AF568$485 / 100μlE20-75471-AF405S$485 / 100μlE20-75471-AF405L$485 / 100μlE20-75471-AF546$485 / 100μlE20-75471-AF594$485 / 100μlE20-75471-AF610$485 / 100μlE20-75471-AF635$485 / 100μlE20-75471-AF647$485 / 100μlE20-75471-AF680$485 / 100μlE20-75471-AF700$485 / 100μlE20-75471-AF750$485 / 100μlE20-75471-AF790$485 / 100μlE20-75471-APC$485 / 100μlE20-75471-PE$485 / 100μlE20-75471-Cy3$485 / 100μlE20-75471-Cy5$485 / 100μlE20-75471-Cy5.5$485 / 100μlE20-75471-Cy7$485 / 100μlE20-75471-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.