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Cell Signal Transduction Research Antibodies

IL-1RII Polyclonal Antibody

E20-75470Cite ID: EN0055603DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight45421Da
Protein NameInterleukin-1 receptor type 2
Human Gene Id7850
Human Swiss Prot NoP27930
Mouse Swiss Prot NoP27931
SpecificityIL-1RII Polyclonal Antibody detects endogenous levels of IL-1RII protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameIL1R2; IL1RB; Interleukin-1 receptor type 2; IL-1R-2; IL-1RT-2; IL-1RT2; CD121 antigen-like family member B; CDw121b; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD121b
Observed Band(KD)43
Functionfunction:Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1ra).,similarity:Belongs to the interleukin-1 receptor family.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,
Subcellular Location[Isoform Short]: Secreted .; [Isoform Long]: Cell membrane; Single-pass type I membrane protein.
ExpressionB-cell,Colon,Ovary,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human IL1R2. AA range:141-190
Gene NameIL1R2
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgroundinterleukin 1 receptor type 2(IL1R2) Homo sapiens The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012],

Conjugated Antibody

This product is also available conjugated. Format: E20-75470-Conjugate. Price: $485 / Size: 100μl.

E20-75470-FITC$485 / 100μlE20-75470-Biotin$485 / 100μlE20-75470-HRP$485 / 100μlE20-75470-AP$485 / 100μlE20-75470-AF350$485 / 100μlE20-75470-AF405M$485 / 100μlE20-75470-AF488$485 / 100μlE20-75470-AF514$485 / 100μlE20-75470-AF532$485 / 100μlE20-75470-AF555$485 / 100μlE20-75470-AF568$485 / 100μlE20-75470-AF405S$485 / 100μlE20-75470-AF405L$485 / 100μlE20-75470-AF546$485 / 100μlE20-75470-AF594$485 / 100μlE20-75470-AF610$485 / 100μlE20-75470-AF635$485 / 100μlE20-75470-AF647$485 / 100μlE20-75470-AF680$485 / 100μlE20-75470-AF700$485 / 100μlE20-75470-AF750$485 / 100μlE20-75470-AF790$485 / 100μlE20-75470-APC$485 / 100μlE20-75470-PE$485 / 100μlE20-75470-Cy3$485 / 100μlE20-75470-Cy5$485 / 100μlE20-75470-Cy5.5$485 / 100μlE20-75470-Cy7$485 / 100μlE20-75470-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.