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Cell Signal Transduction Research Antibodies
CD3-ε Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight23147Da
Protein NameT-cell surface glycoprotein CD3 epsilon chain
Human Gene Id916
Human Swiss Prot NoP07766
Mouse Swiss Prot NoP22646
SpecificityCD3-ε Polyclonal Antibody detects endogenous levels of CD3-ε protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e
Observed Band(KD)23
Functionfunction:The CD3 complex mediates signal transduction.,online information:CD3E mutation db,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 1 ITAM domain.,subunit:The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.,
Subcellular LocationCell membrane ; Single-pass type I membrane protein .
ExpressionBlood,T-cell,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD3E. AA range:31-80
Gene NameCD3E
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
BackgroundCD3e molecule(CD3E) Homo sapiens The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75459-Conjugate. Price: $485 / Size: 100μl.
E20-75459-FITC$485 / 100μlE20-75459-Biotin$485 / 100μlE20-75459-HRP$485 / 100μlE20-75459-AP$485 / 100μlE20-75459-AF350$485 / 100μlE20-75459-AF405M$485 / 100μlE20-75459-AF488$485 / 100μlE20-75459-AF514$485 / 100μlE20-75459-AF532$485 / 100μlE20-75459-AF555$485 / 100μlE20-75459-AF568$485 / 100μlE20-75459-AF405S$485 / 100μlE20-75459-AF405L$485 / 100μlE20-75459-AF546$485 / 100μlE20-75459-AF594$485 / 100μlE20-75459-AF610$485 / 100μlE20-75459-AF635$485 / 100μlE20-75459-AF647$485 / 100μlE20-75459-AF680$485 / 100μlE20-75459-AF700$485 / 100μlE20-75459-AF750$485 / 100μlE20-75459-AF790$485 / 100μlE20-75459-APC$485 / 100μlE20-75459-PE$485 / 100μlE20-75459-Cy3$485 / 100μlE20-75459-Cy5$485 / 100μlE20-75459-Cy5.5$485 / 100μlE20-75459-Cy7$485 / 100μlE20-75459-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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