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Cell Signal Transduction Research Antibodies
SNRPN Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight26400Da
Protein NameSmall nuclear ribonucleoprotein-associated protein N
Human Gene Id6638
Human Swiss Prot NoP63162
Mouse Gene Id20646
Mouse Swiss Prot NoP63163
Rat Gene Id81781
Rat Swiss Prot NoP63164
SpecificitySNRPN Polyclonal Antibody detects endogenous levels of SNRPN protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSNRPN; HCERN3; SMN; Small nuclear ribonucleoprotein-associated protein N; snRNP-N; Sm protein D; Sm-D; Sm protein N; Sm-N; SmN; Tissue-specific-splicing protein
Observed Band(KD)26
Functiondisease:Patients with the autoimmune disease systemic lupus erythematosus (SLE) have autoantibodies directed against some of the individual snRNP polypeptides. The most common autoantigen is called Sm. N bears Sm epitopes.,function:May be involved in tissue-specific alternative RNA processing events.,miscellaneous:Encoded on a bicistronic transcript that encode for two proteins, SNRPN and SNURF.,miscellaneous:Encoded on a bicistronic transcript that encode for two proteins, SNRPN and SNURF. In addition to the primary 1.6-kb bicistronic SNURF-SNRPN transcript, SNURF-only transcript is also detected.,similarity:Belongs to the snRNP SmB/SmN family.,similarity:Belongs to the SNURF family.,subunit:Interacts with TDRD3.,tissue specificity:Expressed in brain and lymphoblasts.,tissue specificity:Expressed in heart, skeletal muscle and lymphoblasts (at protein level). Expressed in brain, pancreas
Subcellular LocationNucleus.
ExpressionExpressed in brain and lymphoblasts.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human SNRPN. AA range:21-70
Gene NameSNRPN
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundsmall nuclear ribonucleoprotein polypeptide N(SNRPN) Homo sapiens The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splici
Conjugated Antibody
This product is also available conjugated. Format: E20-75457-Conjugate. Price: $485 / Size: 100μl.
E20-75457-FITC$485 / 100μlE20-75457-Biotin$485 / 100μlE20-75457-HRP$485 / 100μlE20-75457-AP$485 / 100μlE20-75457-AF350$485 / 100μlE20-75457-AF405M$485 / 100μlE20-75457-AF488$485 / 100μlE20-75457-AF514$485 / 100μlE20-75457-AF532$485 / 100μlE20-75457-AF555$485 / 100μlE20-75457-AF568$485 / 100μlE20-75457-AF405S$485 / 100μlE20-75457-AF405L$485 / 100μlE20-75457-AF546$485 / 100μlE20-75457-AF594$485 / 100μlE20-75457-AF610$485 / 100μlE20-75457-AF635$485 / 100μlE20-75457-AF647$485 / 100μlE20-75457-AF680$485 / 100μlE20-75457-AF700$485 / 100μlE20-75457-AF750$485 / 100μlE20-75457-AF790$485 / 100μlE20-75457-APC$485 / 100μlE20-75457-PE$485 / 100μlE20-75457-Cy3$485 / 100μlE20-75457-Cy5$485 / 100μlE20-75457-Cy5.5$485 / 100μlE20-75457-Cy7$485 / 100μlE20-75457-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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