Rab 5A Polyclonal Antibody

Name: Rab 5A Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75456
Price: 225 USD
Availability: InStock

E20-75456Cite ID: EN0055589Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight23650Da

Protein NameRas-related protein Rab-5A

Human Gene Id5868

Human Swiss Prot NoP20339

Mouse Gene Id271457

Mouse Swiss Prot NoQ9CQD1

SpecificityRab 5A Polyclonal Antibody detects endogenous levels of Rab 5A protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameRAB5A; RAB5; Ras-related protein Rab-5A

Observed Band(KD)24

Functionenzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,function:Required for the fusion of plasma membranes and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, UNC84B, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3.,

Subcellular LocationCell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome membrane ; Lipid-anchor . Melanosome . Cytoplasmic vesicle . Cell projection, ruffle . Membrane . Cytoplasm, cytosol . Cytoplasmic vesicle, phagosome membrane . Endosome membrane . Enriched in stage I melanosomes (PubMed:17081065). Alternates between membrane-bound and cytosolic forms (Probable). .

ExpressionBrain,Cervix,Cervix carcinoma,Placenta,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human RAB5A. AA range:71-120

Gene NameRAB5A

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Backgroundenzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,function:Required for the fusion of plasma membranes and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, UNC84B, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3.,

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75456-Conjugate. Price: $485 / Size: 100μl.

E20-75456-FITC$485 / 100μlE20-75456-Biotin$485 / 100μlE20-75456-HRP$485 / 100μlE20-75456-AP$485 / 100μlE20-75456-AF350$485 / 100μlE20-75456-AF405M$485 / 100μlE20-75456-AF488$485 / 100μlE20-75456-AF514$485 / 100μlE20-75456-AF532$485 / 100μlE20-75456-AF555$485 / 100μlE20-75456-AF568$485 / 100μlE20-75456-AF405S$485 / 100μlE20-75456-AF405L$485 / 100μlE20-75456-AF546$485 / 100μlE20-75456-AF594$485 / 100μlE20-75456-AF610$485 / 100μlE20-75456-AF635$485 / 100μlE20-75456-AF647$485 / 100μlE20-75456-AF680$485 / 100μlE20-75456-AF700$485 / 100μlE20-75456-AF750$485 / 100μlE20-75456-AF790$485 / 100μlE20-75456-APC$485 / 100μlE20-75456-PE$485 / 100μlE20-75456-Cy3$485 / 100μlE20-75456-Cy5$485 / 100μlE20-75456-Cy5.5$485 / 100μlE20-75456-Cy7$485 / 100μlE20-75456-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.