KLK1 Polyclonal Antibody

Name: KLK1 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75449
Price: 225 USD
Availability: InStock

E20-75449Cite ID: EN0055582Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight28820Da

Protein NameKallikrein-1

Human Gene Id3816

Human Swiss Prot NoP06870

Mouse Swiss Prot NoP15947

SpecificityKLK1 Polyclonal Antibody detects endogenous levels of KLK1 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameKLK1; Kallikrein-1; Kidney/pancreas/salivary gland kallikrein; Tissue kallikrein

Observed Band(KD)29

Functioncatalytic activity:Preferential cleavage of Arg-|-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa.,function:Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.,online information:Kallikrein entry,PTM:The O-linked polysaccharides on Ser-93, Ser-104 and Ser-167 are probably the mucin type linked to GalNAc. In PubMed:3163150, GalNAc was detected with the corresponding peptides but not located.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Kallikrein subfamily.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Isoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84.,

Subcellular Locationnucleus,extracellular exosome,

ExpressionIsoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human KLK1. AA range:81-130

Gene NameKLK1

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Backgroundkallikrein 1(KLK1) Homo sapiens Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75449-Conjugate. Price: $485 / Size: 100μl.

E20-75449-FITC$485 / 100μlE20-75449-Biotin$485 / 100μlE20-75449-HRP$485 / 100μlE20-75449-AP$485 / 100μlE20-75449-AF350$485 / 100μlE20-75449-AF405M$485 / 100μlE20-75449-AF488$485 / 100μlE20-75449-AF514$485 / 100μlE20-75449-AF532$485 / 100μlE20-75449-AF555$485 / 100μlE20-75449-AF568$485 / 100μlE20-75449-AF405S$485 / 100μlE20-75449-AF405L$485 / 100μlE20-75449-AF546$485 / 100μlE20-75449-AF594$485 / 100μlE20-75449-AF610$485 / 100μlE20-75449-AF635$485 / 100μlE20-75449-AF647$485 / 100μlE20-75449-AF680$485 / 100μlE20-75449-AF700$485 / 100μlE20-75449-AF750$485 / 100μlE20-75449-AF790$485 / 100μlE20-75449-APC$485 / 100μlE20-75449-PE$485 / 100μlE20-75449-Cy3$485 / 100μlE20-75449-Cy5$485 / 100μlE20-75449-Cy5.5$485 / 100μlE20-75449-Cy7$485 / 100μlE20-75449-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.