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Cell Signal Transduction Research Antibodies

EP1 Polyclonal Antibody

E20-75447Cite ID: EN0055580DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight41801Da
Protein NameProstaglandin E2 receptor EP1 subtype
Human Gene Id5731
Human Swiss Prot NoP34995
Mouse Swiss Prot NoP35375
SpecificityEP1 Polyclonal Antibody detects endogenous levels of EP1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NamePTGER1; Prostaglandin E2 receptor EP1 subtype; PGE receptor EP1 subtype; PGE2 receptor EP1 subtype; Prostanoid EP1 receptor
Observed Band(KD)44
Functionfunction:Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.,PTM:Phosphorylated .,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart.,
Subcellular LocationCell membrane; Multi-pass membrane protein.
ExpressionAbundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human PTGER1. AA range:191-240
Gene NamePTGER1
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundprostaglandin E receptor 1(PTGER1) Homo sapiens The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008],

Conjugated Antibody

This product is also available conjugated. Format: E20-75447-Conjugate. Price: $485 / Size: 100μl.

E20-75447-FITC$485 / 100μlE20-75447-Biotin$485 / 100μlE20-75447-HRP$485 / 100μlE20-75447-AP$485 / 100μlE20-75447-AF350$485 / 100μlE20-75447-AF405M$485 / 100μlE20-75447-AF488$485 / 100μlE20-75447-AF514$485 / 100μlE20-75447-AF532$485 / 100μlE20-75447-AF555$485 / 100μlE20-75447-AF568$485 / 100μlE20-75447-AF405S$485 / 100μlE20-75447-AF405L$485 / 100μlE20-75447-AF546$485 / 100μlE20-75447-AF594$485 / 100μlE20-75447-AF610$485 / 100μlE20-75447-AF635$485 / 100μlE20-75447-AF647$485 / 100μlE20-75447-AF680$485 / 100μlE20-75447-AF700$485 / 100μlE20-75447-AF750$485 / 100μlE20-75447-AF790$485 / 100μlE20-75447-APC$485 / 100μlE20-75447-PE$485 / 100μlE20-75447-Cy3$485 / 100μlE20-75447-Cy5$485 / 100μlE20-75447-Cy5.5$485 / 100μlE20-75447-Cy7$485 / 100μlE20-75447-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.