World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
Eotaxin Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight10732Da
Protein NameEotaxin
Human Gene Id6356
Human Swiss Prot NoP51671
Mouse Gene Id20292
Mouse Swiss Prot NoP48298
Rat Gene Id29397
Rat Swiss Prot NoP97545
SpecificityEotaxin Polyclonal Antibody detects endogenous levels of Eotaxin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCCL11; SCYA11; Eotaxin; C-C motif chemokine 11; Eosinophil chemotactic protein; Small-inducible cytokine A11
Observed Band(KD)11
Functionfunction:In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.,induction:By TNF-alpha, interleukin-1 alpha and interferon gamma.,online information:CCL11 entry,PTM:O-linked glycan consists of a Gal-GalNAc disaccharide which is mofified with up to 2 sialic acid residues.,similarity:Belongs to the intercrine beta (chemokine CC) family.,
Subcellular LocationSecreted .
ExpressionBlood,Foreskin,Lung,Placenta,Small intestine,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CCL11. AA range:41-90
Gene NameCCL11
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundC-C motif chemokine ligand 11(CCL11) Homo sapiens This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-75444-Conjugate. Price: $485 / Size: 100μl.
E20-75444-FITC$485 / 100μlE20-75444-Biotin$485 / 100μlE20-75444-HRP$485 / 100μlE20-75444-AP$485 / 100μlE20-75444-AF350$485 / 100μlE20-75444-AF405M$485 / 100μlE20-75444-AF488$485 / 100μlE20-75444-AF514$485 / 100μlE20-75444-AF532$485 / 100μlE20-75444-AF555$485 / 100μlE20-75444-AF568$485 / 100μlE20-75444-AF405S$485 / 100μlE20-75444-AF405L$485 / 100μlE20-75444-AF546$485 / 100μlE20-75444-AF594$485 / 100μlE20-75444-AF610$485 / 100μlE20-75444-AF635$485 / 100μlE20-75444-AF647$485 / 100μlE20-75444-AF680$485 / 100μlE20-75444-AF700$485 / 100μlE20-75444-AF750$485 / 100μlE20-75444-AF790$485 / 100μlE20-75444-APC$485 / 100μlE20-75444-PE$485 / 100μlE20-75444-Cy3$485 / 100μlE20-75444-Cy5$485 / 100μlE20-75444-Cy5.5$485 / 100μlE20-75444-Cy7$485 / 100μlE20-75444-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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