ECA39 Polyclonal Antibody

Name: ECA39 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75443
Price: 225 USD
Availability: InStock

E20-75443Cite ID: EN0055576Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight42952Da

Protein NameBranched-chain-amino-acid aminotransferase, cytosolic

Human Gene Id586

Human Swiss Prot NoP54687

Mouse Gene Id12035

Mouse Swiss Prot NoP24288

Rat Gene Id29592

Rat Swiss Prot NoP54690

SpecificityECA39 Polyclonal Antibody detects endogenous levels of ECA39 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameBCAT1; BCT1; ECA39; Branched-chain-amino-acid aminotransferase, cytosolic; BCAT(c); Protein ECA39

Observed Band(KD)43

Functioncatalytic activity:2-oxoglutaric acid + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid.,catalytic activity:2-oxoglutaric acid + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamic acid.,catalytic activity:L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.,cofactor:Pyridoxal phosphate.,function:Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.,similarity:Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homodimer.,tissue specificity:During embryogenesis, expressed in the brain and kidney. Overexpressed in C-myc induced tumors such as Burkitt's lymphoma.,

Subcellular LocationCytoplasm.

ExpressionDuring embryogenesis, expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitt's lymphoma.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human BCAT1. AA range:231-280

Gene NameBCAT1

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Backgroundbranched chain amino acid transaminase 1(BCAT1) Homo sapiens This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75443-Conjugate. Price: $485 / Size: 100μl.

E20-75443-FITC$485 / 100μlE20-75443-Biotin$485 / 100μlE20-75443-HRP$485 / 100μlE20-75443-AP$485 / 100μlE20-75443-AF350$485 / 100μlE20-75443-AF405M$485 / 100μlE20-75443-AF488$485 / 100μlE20-75443-AF514$485 / 100μlE20-75443-AF532$485 / 100μlE20-75443-AF555$485 / 100μlE20-75443-AF568$485 / 100μlE20-75443-AF405S$485 / 100μlE20-75443-AF405L$485 / 100μlE20-75443-AF546$485 / 100μlE20-75443-AF594$485 / 100μlE20-75443-AF610$485 / 100μlE20-75443-AF635$485 / 100μlE20-75443-AF647$485 / 100μlE20-75443-AF680$485 / 100μlE20-75443-AF700$485 / 100μlE20-75443-AF750$485 / 100μlE20-75443-AF790$485 / 100μlE20-75443-APC$485 / 100μlE20-75443-PE$485 / 100μlE20-75443-Cy3$485 / 100μlE20-75443-Cy5$485 / 100μlE20-75443-Cy5.5$485 / 100μlE20-75443-Cy7$485 / 100μlE20-75443-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.