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Cell Signal Transduction Research Antibodies
FGF-8 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight26525Da
Protein NameFibroblast growth factor 8
Human Gene Id2253
Human Swiss Prot NoP55075
Mouse Gene Id14179
Mouse Swiss Prot NoP37237
SpecificityFGF-8 Polyclonal Antibody detects endogenous levels of FGF-8 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFGF8; AIGF; Fibroblast growth factor 8; FGF-8; Androgen-induced growth factor; AIGF; Heparin-binding growth factor 8; HBGF-8
Observed Band(KD)26
Functionalternative products:Additional isoforms seem to exist,developmental stage:In adults expression is restricted to the gonads.,disease:Defects in FGF8 are a cause of idiopathic hypogonadotropic hypogonadism (IHH) [MIM:146110]. IHH is defined as a deficiency of the pituitary secretion of follicle-stimulating hormone and luteinizing hormone, which results in the impairment of pubertal maturation and of reproductive function.,disease:Defects in FGF8 are the cause of Kallmann syndrome type 6 (KAL6) [MIM:612702]. Kallmann syndrome is a disorder that associates hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. In some patients ot
Subcellular LocationSecreted.
ExpressionOesophageal carcinoma,Placenta,Prostate,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human FGF8. AA range:141-190
Gene NameFGF8
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundfibroblast growth factor 8(FGF8) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene re
Conjugated Antibody
This product is also available conjugated. Format: E20-75437-Conjugate. Price: $485 / Size: 100μl.
E20-75437-FITC$485 / 100μlE20-75437-Biotin$485 / 100μlE20-75437-HRP$485 / 100μlE20-75437-AP$485 / 100μlE20-75437-AF350$485 / 100μlE20-75437-AF405M$485 / 100μlE20-75437-AF488$485 / 100μlE20-75437-AF514$485 / 100μlE20-75437-AF532$485 / 100μlE20-75437-AF555$485 / 100μlE20-75437-AF568$485 / 100μlE20-75437-AF405S$485 / 100μlE20-75437-AF405L$485 / 100μlE20-75437-AF546$485 / 100μlE20-75437-AF594$485 / 100μlE20-75437-AF610$485 / 100μlE20-75437-AF635$485 / 100μlE20-75437-AF647$485 / 100μlE20-75437-AF680$485 / 100μlE20-75437-AF700$485 / 100μlE20-75437-AF750$485 / 100μlE20-75437-AF790$485 / 100μlE20-75437-APC$485 / 100μlE20-75437-PE$485 / 100μlE20-75437-Cy3$485 / 100μlE20-75437-Cy5$485 / 100μlE20-75437-Cy5.5$485 / 100μlE20-75437-Cy7$485 / 100μlE20-75437-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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