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Cell Signal Transduction Research Antibodies
CyPB Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight23743Da
Protein NamePeptidyl-prolyl cis-trans isomerase B
Human Gene Id5479
Human Swiss Prot NoP23284
Mouse Gene Id19035
Mouse Swiss Prot NoP24369
Rat Gene Id64367
Rat Swiss Prot NoP24368
SpecificityCyPB Polyclonal Antibody detects endogenous levels of CyPB protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NamePPIB; CYPB; Peptidyl-prolyl cis-trans isomerase B; PPIase B; CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLP
Observed Band(KD)24
Functioncatalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,caution:It is uncertain whether Met-1 or Met-9 is the initiator.,enzyme regulation:Cyclosporin A (CsA) inhibits CYPB.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,similarity:Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.,similarity:Contains 1 PPIase cyclophilin-type domain.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
Subcellular LocationVirion . (Microbial infection).; Endoplasmic reticulum lumen . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). .
ExpressionBrain,Fetal brain cortex,Prostate,Skin,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human PPIB. AA range:151-200
Gene NamePPIB
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundpeptidylprolyl isomerase B(PPIB) Homo sapiens The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009],
Conjugated Antibody
This product is also available conjugated. Format: E20-75436-Conjugate. Price: $485 / Size: 100μl.
E20-75436-FITC$485 / 100μlE20-75436-Biotin$485 / 100μlE20-75436-HRP$485 / 100μlE20-75436-AP$485 / 100μlE20-75436-AF350$485 / 100μlE20-75436-AF405M$485 / 100μlE20-75436-AF488$485 / 100μlE20-75436-AF514$485 / 100μlE20-75436-AF532$485 / 100μlE20-75436-AF555$485 / 100μlE20-75436-AF568$485 / 100μlE20-75436-AF405S$485 / 100μlE20-75436-AF405L$485 / 100μlE20-75436-AF546$485 / 100μlE20-75436-AF594$485 / 100μlE20-75436-AF610$485 / 100μlE20-75436-AF635$485 / 100μlE20-75436-AF647$485 / 100μlE20-75436-AF680$485 / 100μlE20-75436-AF700$485 / 100μlE20-75436-AF750$485 / 100μlE20-75436-AF790$485 / 100μlE20-75436-APC$485 / 100μlE20-75436-PE$485 / 100μlE20-75436-Cy3$485 / 100μlE20-75436-Cy5$485 / 100μlE20-75436-Cy5.5$485 / 100μlE20-75436-Cy7$485 / 100μlE20-75436-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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