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Cell Signal Transduction Research Antibodies
c-Myb Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight72341Da
Protein NameTranscriptional activator Myb
Human Gene Id4602
Human Swiss Prot NoP10242
Mouse Gene Id17863
Mouse Swiss Prot NoP06876
Specificityc-Myb Polyclonal Antibody detects endogenous levels of c-Myb protein only when acetylation at K480.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameMYB; Transcriptional activator Myb; Proto-oncogene c-Myb
Observed Band(KD)70
Functiondomain:Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.,function:Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.,PTM:Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.,
Subcellular LocationNucleus .
ExpressionLiver,Placenta,Testis,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from human c-Myb around the non-acetylation site of K480.
Gene NameMYB
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundMYB proto-oncogene, transcription factor(MYB) Homo sapiens This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Conjugated Antibody
This product is also available conjugated. Format: E20-75426-Conjugate. Price: $485 / Size: 100μl.
E20-75426-FITC$485 / 100μlE20-75426-Biotin$485 / 100μlE20-75426-HRP$485 / 100μlE20-75426-AP$485 / 100μlE20-75426-AF350$485 / 100μlE20-75426-AF405M$485 / 100μlE20-75426-AF488$485 / 100μlE20-75426-AF514$485 / 100μlE20-75426-AF532$485 / 100μlE20-75426-AF555$485 / 100μlE20-75426-AF568$485 / 100μlE20-75426-AF405S$485 / 100μlE20-75426-AF405L$485 / 100μlE20-75426-AF546$485 / 100μlE20-75426-AF594$485 / 100μlE20-75426-AF610$485 / 100μlE20-75426-AF635$485 / 100μlE20-75426-AF647$485 / 100μlE20-75426-AF680$485 / 100μlE20-75426-AF700$485 / 100μlE20-75426-AF750$485 / 100μlE20-75426-AF790$485 / 100μlE20-75426-APC$485 / 100μlE20-75426-PE$485 / 100μlE20-75426-Cy3$485 / 100μlE20-75426-Cy5$485 / 100μlE20-75426-Cy5.5$485 / 100μlE20-75426-Cy7$485 / 100μlE20-75426-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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