World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
DRA Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight84505Da
Protein NameChloride anion exchanger
Human Gene Id1811
Human Swiss Prot NoP40879
Mouse Gene Id13487
Mouse Swiss Prot NoQ9WVC8
Rat Gene Id114629
Rat Swiss Prot NoQ924C9
SpecificityDRA Polyclonal Antibody detects endogenous levels of DRA protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSLC26A3; DRA; Chloride anion exchanger; Down-regulated in adenoma; Protein DRA; Solute carrier family 26 member 3
Observed Band(KD)84
Functiondevelopmental stage:Expression is significantly decreased in adenomas (polyps) and adenocarcinomas of the colon.,disease:Defects in SLC26A3 are the cause of congenital chloride diarrhea (CLD) [MIM:214700]. CLD is a disease characterized by voluminous watery stools containing an excess of chloride. The children with this disease are often premature.,function:Chloride/bicarbonate exchanger. Involved in absorbtion of in the colon. Helps mediate electrolyte and fluid absorption.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.,similarity:Contains 1 STAS domain.,subunit:Interacts with PDZK1.,
Subcellular Locationplasma membrane,integral component of plasma membrane,membrane,apical plasma membrane,brush border membrane,sperm midpiece,
ExpressionColon,Lung,Rectum tumor,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the C-terminal region of human DRA.
Gene NameSLC26A3
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundsolute carrier family 26 member 3(SLC26A3) Homo sapiens The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75417-Conjugate. Price: $485 / Size: 100μl.
E20-75417-FITC$485 / 100μlE20-75417-Biotin$485 / 100μlE20-75417-HRP$485 / 100μlE20-75417-AP$485 / 100μlE20-75417-AF350$485 / 100μlE20-75417-AF405M$485 / 100μlE20-75417-AF488$485 / 100μlE20-75417-AF514$485 / 100μlE20-75417-AF532$485 / 100μlE20-75417-AF555$485 / 100μlE20-75417-AF568$485 / 100μlE20-75417-AF405S$485 / 100μlE20-75417-AF405L$485 / 100μlE20-75417-AF546$485 / 100μlE20-75417-AF594$485 / 100μlE20-75417-AF610$485 / 100μlE20-75417-AF635$485 / 100μlE20-75417-AF647$485 / 100μlE20-75417-AF680$485 / 100μlE20-75417-AF700$485 / 100μlE20-75417-AF750$485 / 100μlE20-75417-AF790$485 / 100μlE20-75417-APC$485 / 100μlE20-75417-PE$485 / 100μlE20-75417-Cy3$485 / 100μlE20-75417-Cy5$485 / 100μlE20-75417-Cy5.5$485 / 100μlE20-75417-Cy7$485 / 100μlE20-75417-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits