PD-ECGF Polyclonal Antibody

Name: PD-ECGF Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75414

E20-75414Cite ID: EN0055547Datasheet COA MSDS

SourcePolyclonal, Rabbit

Price on request

Quantity

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight49955Da

Protein NameThymidine phosphorylase

Human Gene Id1890

Human Swiss Prot NoP19971

Mouse Gene Id72962

Mouse Swiss Prot NoQ99N42

Rat Gene Id315219

Rat Swiss Prot NoQ5FVR2

SpecificityPD-ECGF Polyclonal Antibody detects endogenous levels of PD-ECGF protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameTYMP; ECGF1; Thymidine phosphorylase; TP; Gliostatin; Platelet-derived endothelial cell growth factor; PD-ECGF; TdRPase

Observed Band(KD)50

Functioncatalytic activity:Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.,disease:Defects in TYMP are the cause of mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) [MIM:603041]; also known as myoneurogastrointestinal encephalomyopathy. MNGIE is an autosomal recessive disease associated with multiple deletions of skeletal muscle mitochondrial DNA (MtDNA). It is clinically characterized by onset between the second and fifth decades of life, ptosis, progressive external ophthalmoplegia, gastrointestinal dysmotility (often pseudoobstruction), diffuse leukoencephalopathy, thin body habitus, peripheral neuropathy, and myopathy.,function:Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.,function:May have a role in maintaining the in

Subcellular Locationcytosol,

ExpressionBrain,Lung,Placenta,Synovial membrane tissue,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human TYMP. AA range:11-60

Gene NameTYMP

DilutionWestern Blot: 1/500 - 1/2000.IF 1:50-200.IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Backgroundthymidine phosphorylase(TYMP) Homo sapiens This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75414-Conjugate. Price: $485 / Size: 100μl.

E20-75414-FITC$485 / 100μlE20-75414-Biotin$485 / 100μlE20-75414-HRP$485 / 100μlE20-75414-AP$485 / 100μlE20-75414-AF350$485 / 100μlE20-75414-AF405M$485 / 100μlE20-75414-AF488$485 / 100μlE20-75414-AF514$485 / 100μlE20-75414-AF532$485 / 100μlE20-75414-AF555$485 / 100μlE20-75414-AF568$485 / 100μlE20-75414-AF405S$485 / 100μlE20-75414-AF405L$485 / 100μlE20-75414-AF546$485 / 100μlE20-75414-AF594$485 / 100μlE20-75414-AF610$485 / 100μlE20-75414-AF635$485 / 100μlE20-75414-AF647$485 / 100μlE20-75414-AF680$485 / 100μlE20-75414-AF700$485 / 100μlE20-75414-AF750$485 / 100μlE20-75414-AF790$485 / 100μlE20-75414-APC$485 / 100μlE20-75414-PE$485 / 100μlE20-75414-Cy3$485 / 100μlE20-75414-Cy5$485 / 100μlE20-75414-Cy5.5$485 / 100μlE20-75414-Cy7$485 / 100μlE20-75414-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.