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Cell Signal Transduction Research Antibodies
MDA-7 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight):23825Da
Protein NameInterleukin-24
Human Gene Id11009
Human Swiss Prot NoQ13007
Mouse Gene Id93672
Mouse Swiss Prot NoQ925S4
Rat Gene Id170819
Rat Swiss Prot NoQ9JI24
SpecificityMDA-7 Polyclonal Antibody detects endogenous levels of MDA-7 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameIL24; MDA7; ST16; Interleukin-24; IL-24; Melanoma differentiation-associated gene 7 protein; MDA-7; Suppression of tumorigenicity 16 protein
Observed Band(KD)24
Functioncaution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Has antiproliferative properties on melanoma cells and may contribute to terminal cell differentiation.,online information:Interleukin-24 entry,similarity:Belongs to the IL-10 family.,tissue specificity:Up-regulated in melanoma cells induced to terminally differentiate.,
Subcellular Locationextracellular region,extracellular space,
ExpressionFibroblast,Lung,Melanoma,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human IL24. AA range:131-180
Gene NameIL24
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgroundinterleukin 24(IL24) Homo sapiens This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75411-Conjugate. Price: $485 / Size: 100μl.
E20-75411-FITC$485 / 100μlE20-75411-Biotin$485 / 100μlE20-75411-HRP$485 / 100μlE20-75411-AP$485 / 100μlE20-75411-AF350$485 / 100μlE20-75411-AF405M$485 / 100μlE20-75411-AF488$485 / 100μlE20-75411-AF514$485 / 100μlE20-75411-AF532$485 / 100μlE20-75411-AF555$485 / 100μlE20-75411-AF568$485 / 100μlE20-75411-AF405S$485 / 100μlE20-75411-AF405L$485 / 100μlE20-75411-AF546$485 / 100μlE20-75411-AF594$485 / 100μlE20-75411-AF610$485 / 100μlE20-75411-AF635$485 / 100μlE20-75411-AF647$485 / 100μlE20-75411-AF680$485 / 100μlE20-75411-AF700$485 / 100μlE20-75411-AF750$485 / 100μlE20-75411-AF790$485 / 100μlE20-75411-APC$485 / 100μlE20-75411-PE$485 / 100μlE20-75411-Cy3$485 / 100μlE20-75411-Cy5$485 / 100μlE20-75411-Cy5.5$485 / 100μlE20-75411-Cy7$485 / 100μlE20-75411-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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