Product Information
Molecular Weight30084Da
Protein NameCerberus
Human Gene Id9350
Human Swiss Prot NoO95813
Mouse Gene Id12622
Mouse Swiss Prot NoO55233
SpecificityCerberus Polyclonal Antibody detects endogenous levels of Cerberus protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCER1; DAND4; Cerberus; Cerberus-related protein; DAN domain family member 4
Observed Band(KD)30
FunctionCytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak.,PTM:N-glycosylated.,sequence caution:Translated as Ser.,similarity:Belongs to the DAN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,subunit:Forms monomers and predominantly dimers.,
Subcellular Locationextracellular region,extracellular space,
ExpressionBlood,PCR rescued clones,
Backgroundcerberus 1, DAN family BMP antagonist(CER1) Homo sapiens This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008],