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Cell Signal Transduction Research Antibodies

CD158b2/j Polyclonal Antibody

E20-75407Cite ID: EN0055540DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight(Da):37886/33502
Observed Band:
38Da
Protein NameKiller cell immunoglobulin-like receptor 2DL3/Killer cell immunoglobulin-like receptor 2DS2
Human Gene Id3804/100132285
Human Swiss Prot NoP43628/P43631
SpecificityCD158b2/j Polyclonal Antibody detects endogenous levels of CD158b2/j protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameKIR2DL3; CD158B2; KIRCL23; NKAT2; Killer cell immunoglobulin-like receptor 2DL3; CD158 antigen-like family member B2; KIR-023GB; Killer inhibitory receptor cl 2-3; MHC class I NK cell receptor; NKAT2a; NKAT2bNatural killer-associated transcript 2; NKAT-2; p58 natural killer cell receptor clone CL-6; p58 NK receptor CL-6; p58.2 MHC class-I-specific NK receptor; CD158b2; KIR2DS2; CD158J; NKAT5; Killer cell immunoglobulin-like receptor 2DS2;
FunctionReceptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,
Subcellular Locationplasma membrane,integral component of plasma membrane,integral component of membrane,
ExpressionBlood,Natural kille
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human KIR2DL3/KIR2DS2. AA range:131-180
Gene NameKIR2DL3/KIR2DS2
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundkiller cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3(KIR2DL3) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the

Conjugated Antibody

This product is also available conjugated. Format: E20-75407-Conjugate. Price: $485 / Size: 100μl.

E20-75407-FITC$485 / 100μlE20-75407-Biotin$485 / 100μlE20-75407-HRP$485 / 100μlE20-75407-AP$485 / 100μlE20-75407-AF350$485 / 100μlE20-75407-AF405M$485 / 100μlE20-75407-AF488$485 / 100μlE20-75407-AF514$485 / 100μlE20-75407-AF532$485 / 100μlE20-75407-AF555$485 / 100μlE20-75407-AF568$485 / 100μlE20-75407-AF405S$485 / 100μlE20-75407-AF405L$485 / 100μlE20-75407-AF546$485 / 100μlE20-75407-AF594$485 / 100μlE20-75407-AF610$485 / 100μlE20-75407-AF635$485 / 100μlE20-75407-AF647$485 / 100μlE20-75407-AF680$485 / 100μlE20-75407-AF700$485 / 100μlE20-75407-AF750$485 / 100μlE20-75407-AF790$485 / 100μlE20-75407-APC$485 / 100μlE20-75407-PE$485 / 100μlE20-75407-Cy3$485 / 100μlE20-75407-Cy5$485 / 100μlE20-75407-Cy5.5$485 / 100μlE20-75407-Cy7$485 / 100μlE20-75407-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.