Product Information
Molecular Weight159239Da
Protein NameScavenger receptor cysteine-rich type 1 protein M160
Human Gene Id283316
Human Swiss Prot NoQ9NR16
SpecificityCD163b Polyclonal Antibody detects endogenous levels of CD163b protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD163L1; CD163B; M160; Scavenger receptor cysteine-rich type 1 protein M160; CD163 antigen-like 1; CD163b
Observed Band(KD)160
Functionsimilarity:Contains 12 SRCR domains.,tissue specificity:Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and macrophage cell lines. Isoform 2 is only expressed in spleen.,
Subcellular Locationextracellular region,plasma membrane,membrane,integral component of membrane,
ExpressionLiver,Lung and heart,
BackgroundCD163 molecule like 1(CD163L1) Homo sapiens This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],