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Cell Signal Transduction Research Antibodies
DNAM-1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight38584Da
Protein NameCD226 antigen
Human Gene Id10666
Human Swiss Prot NoQ15762
Mouse Gene Id225825
Mouse Swiss Prot NoQ8K4F0
SpecificityDNAM-1 Polyclonal Antibody detects endogenous levels of DNAM-1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD226; DNAM1; CD226 antigen; DNAX accessory molecule 1; DNAM-1; CD226
Observed Band(KD)38
FunctionReceptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.,PTM:Phosphorylated.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with PVR and PVRL2.,tissue specificity:Expressed by peripheral blood T-lymphocytes.,
Subcellular Locationplasma membrane,integral component of plasma membrane,cell-cell adherens junction,external side of plasma membrane,cell surface,integral component of membrane,membrane raft,
ExpressionBrain,Natural killer cell,Platelet,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD226. AA range:71-120
Gene NameCD226
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundCD226 molecule(CD226) Homo sapiens This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
Conjugated Antibody
This product is also available conjugated. Format: E20-75402-Conjugate. Price: $485 / Size: 100μl.
E20-75402-FITC$485 / 100μlE20-75402-Biotin$485 / 100μlE20-75402-HRP$485 / 100μlE20-75402-AP$485 / 100μlE20-75402-AF350$485 / 100μlE20-75402-AF405M$485 / 100μlE20-75402-AF488$485 / 100μlE20-75402-AF514$485 / 100μlE20-75402-AF532$485 / 100μlE20-75402-AF555$485 / 100μlE20-75402-AF568$485 / 100μlE20-75402-AF405S$485 / 100μlE20-75402-AF405L$485 / 100μlE20-75402-AF546$485 / 100μlE20-75402-AF594$485 / 100μlE20-75402-AF610$485 / 100μlE20-75402-AF635$485 / 100μlE20-75402-AF647$485 / 100μlE20-75402-AF680$485 / 100μlE20-75402-AF700$485 / 100μlE20-75402-AF750$485 / 100μlE20-75402-AF790$485 / 100μlE20-75402-APC$485 / 100μlE20-75402-PE$485 / 100μlE20-75402-Cy3$485 / 100μlE20-75402-Cy5$485 / 100μlE20-75402-Cy5.5$485 / 100μlE20-75402-Cy7$485 / 100μlE20-75402-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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