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Cell Signal Transduction Research Antibodies
CD81 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight25809Da
Protein NameCD81 antigen
Human Gene Id975
Human Swiss Prot NoP60033
Mouse Gene Id12520
Mouse Swiss Prot NoP35762
Rat Gene Id25621
Rat Swiss Prot NoQ62745
SpecificityCD81 Polyclonal Antibody detects endogenous levels of CD81 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD81; TAPA1; TSPAN28; CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; Tetraspanin-28; Tspan-28; CD81
Observed Band(KD)26
FunctionMay play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May acts a the viral receptor for HCV.,PTM:Not glycosylated.,similarity:Belongs to the tetraspanin (TM4SF) family.,subunit:Plays a critical role in HCV attachment and/or cell entry by interacting with HCV E1/E2 glycoproteins heterodimer. Interacts directly with IGSF8.,tissue specificity:Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.,
Subcellular LocationCell membrane ; Multi-pass membrane protein . Basolateral cell membrane ; Multi-pass membrane protein . Associates with CLDN1 and the CLDN1-CD81 complex localizes to the basolateral cell membrane. .
ExpressionExpressed on B cells (at protein level) (PubMed:20237408). Expressed in hepatocytes (at protein level) (PubMed:12483205). Expressed in monocytes/macrophages (at protein level) (PubMed:12796480). Expressed on both naive and memory CD4-positive T cells (at protein level) (PubMed:22307619).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD81. AA range:111-160
Gene NameCD81
DilutionIF: 1:50-200 Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundCD81 molecule(CD81) Homo sapiens The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-75394-Conjugate. Price: $485 / Size: 100μl.
E20-75394-FITC$485 / 100μlE20-75394-Biotin$485 / 100μlE20-75394-HRP$485 / 100μlE20-75394-AP$485 / 100μlE20-75394-AF350$485 / 100μlE20-75394-AF405M$485 / 100μlE20-75394-AF488$485 / 100μlE20-75394-AF514$485 / 100μlE20-75394-AF532$485 / 100μlE20-75394-AF555$485 / 100μlE20-75394-AF568$485 / 100μlE20-75394-AF405S$485 / 100μlE20-75394-AF405L$485 / 100μlE20-75394-AF546$485 / 100μlE20-75394-AF594$485 / 100μlE20-75394-AF610$485 / 100μlE20-75394-AF635$485 / 100μlE20-75394-AF647$485 / 100μlE20-75394-AF680$485 / 100μlE20-75394-AF700$485 / 100μlE20-75394-AF750$485 / 100μlE20-75394-AF790$485 / 100μlE20-75394-APC$485 / 100μlE20-75394-PE$485 / 100μlE20-75394-Cy3$485 / 100μlE20-75394-Cy5$485 / 100μlE20-75394-Cy5.5$485 / 100μlE20-75394-Cy7$485 / 100μlE20-75394-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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