Product Information
Molecular Weight55110Da
Protein NameSolute carrier family 2 facilitated glucose transporter member 5
Human Gene Id6518
Human Swiss Prot NoP22732
Mouse Swiss Prot NoQ9WV38
SpecificityGlut5 Polyclonal Antibody detects endogenous levels of Glut5 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSLC2A5; GLUT5; Solute carrier family 2, facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5
Observed Band(KD)55
FunctionCytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.,induction:By forskolin (in Caco-2 cells).,mass spectrometry: PubMed:11840567,similarity:Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.,tissue specificity:Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.,
Subcellular LocationApical cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma . Localized on the apical membrane of jejunum villi, but also on lateral plasma membranes of the villi. Transport to the cell membrane is dependent on RAB11A. .
ExpressionDetected in skeletal muscle, and in jejunum brush border membrane and basolateral membrane (at protein level) (PubMed:7619085). Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.
Backgroundsolute carrier family 2 member 5(SLC2A5) Homo sapiens The protein encoded by this gene is a fructose transporter responsible for fructose uptake by the small intestine. The encoded protein also is necessary for the increase in blood pressure due to high dietary fructose consumption. [provided by RefSeq, Jun 2016],