Product Information
Molecular Weight61930Da
Protein NameSolute carrier family 22 member 6
Human Gene Id9356
Human Swiss Prot NoQ4U2R8
Mouse Swiss Prot NoQ8VC69
SpecificityOAT1 Polyclonal Antibody detects endogenous levels of OAT1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSLC22A6; OAT1; PAHT; Solute carrier family 22 member 6; Organic anion transporter 1; hOAT1; PAH transporter; hPAHT; Renal organic anion transporter 1; hROAT1
Observed Band(KD)70
Subcellular LocationCell membrane ; Multi-pass membrane protein .
ExpressionStrongly expressed in kidney and to a lower extent in liver, skeletal muscle, brain and placenta. Found at the basolateral membrane of the proximal tubule.
BackgroundSolute carrier family 22 member 6 encoded by SLC22A6 is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene.