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Cell Signal Transduction Research Antibodies

IL-2Rγ Polyclonal Antibody

E20-75380Cite ID: EN0055513DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight42287Da
Protein NameCytokine receptor common subunit gamma
Human Gene Id3561
Human Swiss Prot NoP31785
Mouse Swiss Prot NoP34902
SpecificityIL-2Rγ Polyclonal Antibody detects endogenous levels of IL-2Rγ protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameIL2RG; Cytokine receptor common subunit gamma; Interleukin-2 receptor subunit gamma; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; gammaC; p64; CD132
Observed Band(KD)40
Functiondisease:Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID) [MIM:312863]. XCID is a less severe form of X-linked immunodeficiency with a less severe degree of deficiency in cellular and humoral immunity than that seen in XSCID.,disease:Defects in IL2RG are the cause of X-linked severe combined immunodeficiency (XSCID) [MIM:300400]; also known as agammaglobulinemia Swiss type. SCID refers to a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. Patients with SCID present in infancy with recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development.,domain:The box 1 motif is required for JAK inte
Subcellular LocationCell membrane ; Single-pass type I membrane protein . Cell surface .
ExpressionB-cell,Liver,Peripheral blood,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human IL2RG. AA range:101-150
Gene NameIL2RG
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundinterleukin 2 receptor subunit gamma(IL2RG) Homo sapiens The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010],

Conjugated Antibody

This product is also available conjugated. Format: E20-75380-Conjugate. Price: $485 / Size: 100μl.

E20-75380-FITC$485 / 100μlE20-75380-Biotin$485 / 100μlE20-75380-HRP$485 / 100μlE20-75380-AP$485 / 100μlE20-75380-AF350$485 / 100μlE20-75380-AF405M$485 / 100μlE20-75380-AF488$485 / 100μlE20-75380-AF514$485 / 100μlE20-75380-AF532$485 / 100μlE20-75380-AF555$485 / 100μlE20-75380-AF568$485 / 100μlE20-75380-AF405S$485 / 100μlE20-75380-AF405L$485 / 100μlE20-75380-AF546$485 / 100μlE20-75380-AF594$485 / 100μlE20-75380-AF610$485 / 100μlE20-75380-AF635$485 / 100μlE20-75380-AF647$485 / 100μlE20-75380-AF680$485 / 100μlE20-75380-AF700$485 / 100μlE20-75380-AF750$485 / 100μlE20-75380-AF790$485 / 100μlE20-75380-APC$485 / 100μlE20-75380-PE$485 / 100μlE20-75380-Cy3$485 / 100μlE20-75380-Cy5$485 / 100μlE20-75380-Cy5.5$485 / 100μlE20-75380-Cy7$485 / 100μlE20-75380-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.