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Cell Signal Transduction Research Antibodies
Connexin-40 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight40380Da
Protein NameGap junction alpha-5 protein
Human Gene Id2702
Human Swiss Prot NoP36382
Mouse Gene Id14613
Mouse Swiss Prot NoQ01231
Rat Gene Id50563
Rat Swiss Prot NoP28234
SpecificityConnexin-40 Polyclonal Antibody detects endogenous levels of Connexin-40 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameGJA5; Gap junction alpha-5 protein; Connexin-40; Cx40
Observed Band(KD)39
Functiondisease:Defects in GJA5 are a cause of idiopathic atrial fibrillation [MIM:108770]. Atrial fibrillation (AF) is the most common cardiac arrhythmia and is characterized by rapid and irregular activation of the atrium.,function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Alpha-type (group II) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,
Subcellular LocationCell membrane; Multi-pass membrane protein. Cell junction, gap junction.
ExpressionPlacenta,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human GJA5. AA range:21-70
Gene NameGJA5
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundgap junction protein alpha 5(GJA5) Homo sapiens This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75377-Conjugate. Price: $485 / Size: 100μl.
E20-75377-FITC$485 / 100μlE20-75377-Biotin$485 / 100μlE20-75377-HRP$485 / 100μlE20-75377-AP$485 / 100μlE20-75377-AF350$485 / 100μlE20-75377-AF405M$485 / 100μlE20-75377-AF488$485 / 100μlE20-75377-AF514$485 / 100μlE20-75377-AF532$485 / 100μlE20-75377-AF555$485 / 100μlE20-75377-AF568$485 / 100μlE20-75377-AF405S$485 / 100μlE20-75377-AF405L$485 / 100μlE20-75377-AF546$485 / 100μlE20-75377-AF594$485 / 100μlE20-75377-AF610$485 / 100μlE20-75377-AF635$485 / 100μlE20-75377-AF647$485 / 100μlE20-75377-AF680$485 / 100μlE20-75377-AF700$485 / 100μlE20-75377-AF750$485 / 100μlE20-75377-AF790$485 / 100μlE20-75377-APC$485 / 100μlE20-75377-PE$485 / 100μlE20-75377-Cy3$485 / 100μlE20-75377-Cy5$485 / 100μlE20-75377-Cy5.5$485 / 100μlE20-75377-Cy7$485 / 100μlE20-75377-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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