World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies

ALPP/ALPPL2 Polyclonal Antibody

E20-75375Cite ID: EN0055508DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight57954/57377Da
Protein NameAlkaline phosphatase, placental type/Alkaline phosphatase, placental-like
Human Gene Id250/251
Human Swiss Prot NoP05187/P10696
Mouse Gene Id11650
SpecificityALPP/ALPPL2 Polyclonal Antibody detects endogenous levels of ALPP/ALPPL2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameALPP; PLAP; Alkaline phosphatase, placental type; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1; ALPPL2; ALPPL; Alkaline phosphatase, placental-likeALP-1; Alkaline phosphatase Nagao isozyme; Germ cell alkaline phosphatase; GCAP; Placental alkaline phosphatase-like; PLAP-like
Observed Band(KD)60
Functioncatalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,cofactor:Binds 1 magnesium ion.,cofactor:Binds 2 zinc ions.,miscellaneous:In most mammals there are four different isozymes: placental, placental-like, intestinal and tissue non-specific (liver/bone/kidney).,online information:Alkaline phosphatase entry,polymorphism:Placental ALP is highly polymorphic, there are at least three common alleles.,similarity:Belongs to the alkaline phosphatase family.,subunit:Homodimer.,
Subcellular LocationCell membrane; Lipid-anchor, GPI-anchor .
ExpressionDetected in placenta (at protein level).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human ALPP/ALPPL2. AA range:1-50
Gene NameALPP/ALPPL2
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundalkaline phosphatase, placental(ALPP) Homo sapiens The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015],

Conjugated Antibody

This product is also available conjugated. Format: E20-75375-Conjugate. Price: $485 / Size: 100μl.

E20-75375-FITC$485 / 100μlE20-75375-Biotin$485 / 100μlE20-75375-HRP$485 / 100μlE20-75375-AP$485 / 100μlE20-75375-AF350$485 / 100μlE20-75375-AF405M$485 / 100μlE20-75375-AF488$485 / 100μlE20-75375-AF514$485 / 100μlE20-75375-AF532$485 / 100μlE20-75375-AF555$485 / 100μlE20-75375-AF568$485 / 100μlE20-75375-AF405S$485 / 100μlE20-75375-AF405L$485 / 100μlE20-75375-AF546$485 / 100μlE20-75375-AF594$485 / 100μlE20-75375-AF610$485 / 100μlE20-75375-AF635$485 / 100μlE20-75375-AF647$485 / 100μlE20-75375-AF680$485 / 100μlE20-75375-AF700$485 / 100μlE20-75375-AF750$485 / 100μlE20-75375-AF790$485 / 100μlE20-75375-APC$485 / 100μlE20-75375-PE$485 / 100μlE20-75375-Cy3$485 / 100μlE20-75375-Cy5$485 / 100μlE20-75375-Cy5.5$485 / 100μlE20-75375-Cy7$485 / 100μlE20-75375-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.