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Cell Signal Transduction Research Antibodies

Annexin VII Polyclonal Antibody

E20-75373Cite ID: EN0055506DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight52739Da
Protein NameAnnexin A7
Human Gene Id310
Human Swiss Prot NoP20073
Mouse Gene Id11750
Mouse Swiss Prot NoQ07076
SpecificityAnnexin VII Polyclonal Antibody detects endogenous levels of Annexin VII protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameANXA7; ANX7; SNX; OK/SW-cl.95; Annexin A7; Annexin VII; Annexin-7; Synexin
Observed Band(KD)53
Functiondomain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,function:Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,tissue specificity:Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta.,
Subcellular Locationnucleus,nuclear envelope,endoplasmic reticulum membrane,cytosol,plasma membrane,membrane,chromaffin granule membrane,extracellular exosome,
ExpressionIsoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human ANXA7. AA range:271-320
Gene NameANXA7
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgroundannexin A7(ANXA7) Homo sapiens Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the

Conjugated Antibody

This product is also available conjugated. Format: E20-75373-Conjugate. Price: $485 / Size: 100μl.

E20-75373-FITC$485 / 100μlE20-75373-Biotin$485 / 100μlE20-75373-HRP$485 / 100μlE20-75373-AP$485 / 100μlE20-75373-AF350$485 / 100μlE20-75373-AF405M$485 / 100μlE20-75373-AF488$485 / 100μlE20-75373-AF514$485 / 100μlE20-75373-AF532$485 / 100μlE20-75373-AF555$485 / 100μlE20-75373-AF568$485 / 100μlE20-75373-AF405S$485 / 100μlE20-75373-AF405L$485 / 100μlE20-75373-AF546$485 / 100μlE20-75373-AF594$485 / 100μlE20-75373-AF610$485 / 100μlE20-75373-AF635$485 / 100μlE20-75373-AF647$485 / 100μlE20-75373-AF680$485 / 100μlE20-75373-AF700$485 / 100μlE20-75373-AF750$485 / 100μlE20-75373-AF790$485 / 100μlE20-75373-APC$485 / 100μlE20-75373-PE$485 / 100μlE20-75373-Cy3$485 / 100μlE20-75373-Cy5$485 / 100μlE20-75373-Cy5.5$485 / 100μlE20-75373-Cy7$485 / 100μlE20-75373-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.