MCM7 Polyclonal Antibody

Name: MCM7 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75371
Price: 225 USD
Availability: InStock

E20-75371Cite ID: EN0055504Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight81308Da

Protein NameDNA replication licensing factor MCM7

Human Gene Id4176

Human Swiss Prot NoP33993

Mouse Gene Id17220

Mouse Swiss Prot NoQ61881

SpecificityMCM7 Polyclonal Antibody detects endogenous levels of MCM7 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameMCM7; CDC47; MCM2; DNA replication licensing factor MCM7; CDC47 homolog; P1.1-MCM3

Observed Band(KD)81

FunctionActs as a factor that allows the DNA to undergo a single round of replication per cell cycle. Required for DNA replication and cell proliferation. Required for S-phase checkpoint activation upon UV-induced damage.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MCM family.,similarity:Contains 1 MCM domain.,subunit:Interacts with the ATR-ATRIP complex and with RAD17. Interacts with TIPIN.,

Subcellular LocationNucleus . Chromosome . Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses. .

ExpressionBrain,Cervix,Chronic myeloid leukemia cell,Lung,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human MCM7. AA range:491-540

Gene NameMCM7

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Backgroundminichromosome maintenance complex component 7(MCM7) Homo sapiens The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75371-Conjugate. Price: $485 / Size: 100μl.

E20-75371-FITC$485 / 100μlE20-75371-Biotin$485 / 100μlE20-75371-HRP$485 / 100μlE20-75371-AP$485 / 100μlE20-75371-AF350$485 / 100μlE20-75371-AF405M$485 / 100μlE20-75371-AF488$485 / 100μlE20-75371-AF514$485 / 100μlE20-75371-AF532$485 / 100μlE20-75371-AF555$485 / 100μlE20-75371-AF568$485 / 100μlE20-75371-AF405S$485 / 100μlE20-75371-AF405L$485 / 100μlE20-75371-AF546$485 / 100μlE20-75371-AF594$485 / 100μlE20-75371-AF610$485 / 100μlE20-75371-AF635$485 / 100μlE20-75371-AF647$485 / 100μlE20-75371-AF680$485 / 100μlE20-75371-AF700$485 / 100μlE20-75371-AF750$485 / 100μlE20-75371-AF790$485 / 100μlE20-75371-APC$485 / 100μlE20-75371-PE$485 / 100μlE20-75371-Cy3$485 / 100μlE20-75371-Cy5$485 / 100μlE20-75371-Cy5.5$485 / 100μlE20-75371-Cy7$485 / 100μlE20-75371-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.