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Cell Signal Transduction Research Antibodies
L-Selectin Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight42187Da
Protein NameL-selectin
Human Gene Id6402
Human Swiss Prot NoP14151
Mouse Gene Id20343
Mouse Swiss Prot NoP18337
Rat Swiss Prot NoP30836
SpecificityL-Selectin Polyclonal Antibody detects endogenous levels of L-Selectin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSELL; LNHR; LYAM1; L-selectin; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; TQ1; gp90-MEL; CD62L
Observed Band(KD)42
FunctionCell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.,online information:L-selectin,similarity:Belongs to the selectin/LECAM family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 2 Sushi (CCP/SCR) domains.,subunit:Interaction with PSGL1/SELPLG is required for promoting recruitment and rolling of leukocytes. This interaction is dependent on the sialyl Lewis X glycan and tyrosine sulfation modifications of PSGL1. Sulfation on Y-51 of PSGL1 is important for L-selectin binding.,tissue specificity:Expressed in B cell lines and T lymphocytes.,
Subcellular LocationCell membrane ; Single-pass type I membrane protein .
ExpressionExpressed in B-cell lines and T-lymphocytes.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human SELL. AA range:91-140
Gene NameSELL
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundselectin L(SELL) Homo sapiens This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009],
Conjugated Antibody
This product is also available conjugated. Format: E20-75370-Conjugate. Price: $485 / Size: 100μl.
E20-75370-FITC$485 / 100μlE20-75370-Biotin$485 / 100μlE20-75370-HRP$485 / 100μlE20-75370-AP$485 / 100μlE20-75370-AF350$485 / 100μlE20-75370-AF405M$485 / 100μlE20-75370-AF488$485 / 100μlE20-75370-AF514$485 / 100μlE20-75370-AF532$485 / 100μlE20-75370-AF555$485 / 100μlE20-75370-AF568$485 / 100μlE20-75370-AF405S$485 / 100μlE20-75370-AF405L$485 / 100μlE20-75370-AF546$485 / 100μlE20-75370-AF594$485 / 100μlE20-75370-AF610$485 / 100μlE20-75370-AF635$485 / 100μlE20-75370-AF647$485 / 100μlE20-75370-AF680$485 / 100μlE20-75370-AF700$485 / 100μlE20-75370-AF750$485 / 100μlE20-75370-AF790$485 / 100μlE20-75370-APC$485 / 100μlE20-75370-PE$485 / 100μlE20-75370-Cy3$485 / 100μlE20-75370-Cy5$485 / 100μlE20-75370-Cy5.5$485 / 100μlE20-75370-Cy7$485 / 100μlE20-75370-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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