Product Information
Molecular Weight25322Da
Protein NameInsulin-like growth factor-binding protein 6
Human Gene Id3489
Human Swiss Prot NoP24592
Mouse Swiss Prot NoP47880
SpecificityIGFBP6 Polyclonal Antibody detects endogenous levels of IGFBP6 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameIGFBP6; IBP6; Insulin-like growth factor-binding protein 6; IBP-6; IGF-binding protein 6; IGFBP-6
Observed Band(KD)25
FunctionIGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.,PTM:O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. Major glycoforms consist of 8-16 monosaccharides (by homology to IGFBP6 expressed recombinantly in CHO cells).,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 thyroglobulin type-1 domain.,
Subcellular LocationSecreted .
ExpressionCerebrospinal fluid,Fibroblast,Osteosarcoma,Pancreas,Placen