Cytokeratin 19 Polyclonal Antibody

Name: Cytokeratin 19 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75349
Price: 225 USD
Availability: InStock

E20-75349Cite ID: EN0055482Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight44092/59511/53511Da

Protein NameKeratin type I cytoskeletal 19

Human Gene Id3880

Human Swiss Prot NoP08727

Mouse Swiss Prot NoP19001

SpecificityCytokeratin 19 Polyclonal Antibody detects endogenous levels of Cytokeratin 19 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameKRT19; Keratin, type I cytoskeletal 19; Cytokeratin-19; CK-19; Keratin-19; K19

Observed Band(KD)44

Functiondevelopmental stage:Present in hair follicles at all stages of development.,domain:This keratin differs from all other IF proteins in lacking the C-terminal tail domain.,function:Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. Interacts with PNN and the actin-binding domain of DMD. Interacts with HCV core protein.,tissue specificity:Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestin

Subcellular Locationintermediate filament,plasma membrane,dystrophin-associated glycoprotein complex,Z disc,sarcolemma,costamere,extracellular exosome,cell periphery,terminal web,

ExpressionExpressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human KRT19. AA range:321-370

Gene NameKRT19

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Backgroundkeratin 19(KRT19) Homo sapiens The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75349-Conjugate. Price: $485 / Size: 100μl.

E20-75349-FITC$485 / 100μlE20-75349-Biotin$485 / 100μlE20-75349-HRP$485 / 100μlE20-75349-AP$485 / 100μlE20-75349-AF350$485 / 100μlE20-75349-AF405M$485 / 100μlE20-75349-AF488$485 / 100μlE20-75349-AF514$485 / 100μlE20-75349-AF532$485 / 100μlE20-75349-AF555$485 / 100μlE20-75349-AF568$485 / 100μlE20-75349-AF405S$485 / 100μlE20-75349-AF405L$485 / 100μlE20-75349-AF546$485 / 100μlE20-75349-AF594$485 / 100μlE20-75349-AF610$485 / 100μlE20-75349-AF635$485 / 100μlE20-75349-AF647$485 / 100μlE20-75349-AF680$485 / 100μlE20-75349-AF700$485 / 100μlE20-75349-AF750$485 / 100μlE20-75349-AF790$485 / 100μlE20-75349-APC$485 / 100μlE20-75349-PE$485 / 100μlE20-75349-Cy3$485 / 100μlE20-75349-Cy5$485 / 100μlE20-75349-Cy5.5$485 / 100μlE20-75349-Cy7$485 / 100μlE20-75349-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.