HNF-4α/γ Polyclonal Antibody

Name: HNF-4α/γ Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75326
Price: 225 USD
Availability: InStock

E20-75326Cite ID: EN0055459Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight52785Da

Protein NameHepatocyte nuclear factor 4-alpha/Hepatocyte nuclear factor 4-gamma

Human Gene Id3172

Human Swiss Prot NoP41235

Mouse Gene Id15378

Mouse Swiss Prot NoP49698

Rat Gene Id25735

Rat Swiss Prot NoP22449

SpecificityHNF-4α/γ Polyclonal Antibody detects endogenous levels of HNF-4α/γ protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameHNF4A; HNF4; NR2A1; TCF14; Hepatocyte nuclear factor 4-alpha; HNF-4-alpha; Nuclear receptor subfamily 2 group A member 1; Transcription factor 14; TCF-14;Transcription factor HNF-4; HNF4G; NR2A2; Hepatocyte nuclear factor 4-gamma; HNF-4-gamma; Nuclear receptor subfamily 2 group A member 2

Observed Band(KD)52

Functionalternative products:Additional isoforms seem to exist,disease:Defects in HNF4A are the cause of maturity onset diabetes of the young type 1 (MODY1) [MIM:125850]; also shortened MODY-1. MODY [MIM:606391] is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age) and a primary defect in insulin secretion. The clinical phenotype of MODY1 is characterized by severe insulin secretory defects, and by major hyperglycemia associated with microvascular complications.,function:Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1-antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1-alpha. May be essential for development of the liver, kidney and intestine.,miscellaneous:Binds fatty acids.,online information:Hepatocyte nuclear fac

Subcellular LocationNucleus.

ExpressionKidney,Liver,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenSynthesized peptide derived from human HNF-4α/γ around the non-acetylation site of K127.

Gene NameHNF4A/HNF4G

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Backgroundhepatocyte nuclear factor 4 alpha(HNF4A) Homo sapiens The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75326-Conjugate. Price: $485 / Size: 100μl.

E20-75326-FITC$485 / 100μlE20-75326-Biotin$485 / 100μlE20-75326-HRP$485 / 100μlE20-75326-AP$485 / 100μlE20-75326-AF350$485 / 100μlE20-75326-AF405M$485 / 100μlE20-75326-AF488$485 / 100μlE20-75326-AF514$485 / 100μlE20-75326-AF532$485 / 100μlE20-75326-AF555$485 / 100μlE20-75326-AF568$485 / 100μlE20-75326-AF405S$485 / 100μlE20-75326-AF405L$485 / 100μlE20-75326-AF546$485 / 100μlE20-75326-AF594$485 / 100μlE20-75326-AF610$485 / 100μlE20-75326-AF635$485 / 100μlE20-75326-AF647$485 / 100μlE20-75326-AF680$485 / 100μlE20-75326-AF700$485 / 100μlE20-75326-AF750$485 / 100μlE20-75326-AF790$485 / 100μlE20-75326-APC$485 / 100μlE20-75326-PE$485 / 100μlE20-75326-Cy3$485 / 100μlE20-75326-Cy5$485 / 100μlE20-75326-Cy5.5$485 / 100μlE20-75326-Cy7$485 / 100μlE20-75326-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.