World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
IDH3A Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight39592Da
Protein NameIsocitrate dehydrogenase [NAD] subunit alpha mitochondrial
Human Gene Id3419
Human Swiss Prot NoP50213
Mouse Gene Id67834
Mouse Swiss Prot NoQ9D6R2
Rat Gene Id114096
Rat Swiss Prot NoQ99NA5
SpecificityIDH3A Polyclonal Antibody detects endogenous levels of IDH3A protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameIDH3A; Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha
Observed Band(KD)39
Functioncatalytic activity:Isocitrate + NAD(+) = 2-oxoglutarate + CO(2) + NADH.,cofactor:Binds 1 magnesium or manganese ion per subunit.,similarity:Belongs to the isocitrate and isopropylmalate dehydrogenases family.,subunit:Heterooligomer of subunits alpha, beta, and gamma in the apparent ratio of 2:1:1.,
Subcellular LocationMitochondrion.
ExpressionBrain,Brain cortex,Cajal-Retzius cell,Esophagus tumor,Fetal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the Internal region of human IDH3A.
Gene NameIDH3A
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgroundisocitrate dehydrogenase 3 (NAD(+)) alpha(IDH3A) Homo sapiens Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75318-Conjugate. Price: $485 / Size: 100μl.
E20-75318-FITC$485 / 100μlE20-75318-Biotin$485 / 100μlE20-75318-HRP$485 / 100μlE20-75318-AP$485 / 100μlE20-75318-AF350$485 / 100μlE20-75318-AF405M$485 / 100μlE20-75318-AF488$485 / 100μlE20-75318-AF514$485 / 100μlE20-75318-AF532$485 / 100μlE20-75318-AF555$485 / 100μlE20-75318-AF568$485 / 100μlE20-75318-AF405S$485 / 100μlE20-75318-AF405L$485 / 100μlE20-75318-AF546$485 / 100μlE20-75318-AF594$485 / 100μlE20-75318-AF610$485 / 100μlE20-75318-AF635$485 / 100μlE20-75318-AF647$485 / 100μlE20-75318-AF680$485 / 100μlE20-75318-AF700$485 / 100μlE20-75318-AF750$485 / 100μlE20-75318-AF790$485 / 100μlE20-75318-APC$485 / 100μlE20-75318-PE$485 / 100μlE20-75318-Cy3$485 / 100μlE20-75318-Cy5$485 / 100μlE20-75318-Cy5.5$485 / 100μlE20-75318-Cy7$485 / 100μlE20-75318-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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