Product Information
Molecular Weight61579Da
Protein NameZinc finger protein with KRAB and SCAN domains 4
Human Gene Id387032
Human Swiss Prot NoQ969J2
SpecificityZKSCAN4 Polyclonal Antibody detects endogenous levels of ZKSCAN4 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameZKSCAN4; ZNF307; ZNF427; Zinc finger protein with KRAB and SCAN domains 4; P373c6.1; Zinc finger protein 307; Zinc finger protein 427
Observed Band(KD)61
Functionfunction:May be involved in the transcriptional activation of MDM2 and EP300 genes.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 1 SCAN box domain.,similarity:Contains 7 C2H2-type zinc fingers.,tissue specificity:Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.,
Subcellular LocationNucleus .
ExpressionExpressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.
Backgroundfunction:May be involved in the transcriptional activation of MDM2 and EP300 genes.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 1 SCAN box domain.,similarity:Contains 7 C2H2-type zinc fingers.,tissue specificity:Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.,