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Cell Signal Transduction Research Antibodies
ARP Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight20700Da
Protein NameMesencephalic astrocyte-derived neurotrophic factor
Human Gene Id7873
Human Swiss Prot NoP55145
Mouse Swiss Prot NoQ9CXI5
Rat Swiss Prot NoP0C5H9
SpecificityARP Polyclonal Antibody detects endogenous levels of ARP protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameMANF; ARMET; ARP; Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; Protein ARMET
Observed Band(KD)20
Functionresponse to unfolded protein, response to organic substance, response to protein stimulus,
Subcellular LocationSecreted . Endoplasmic reticulum lumen . Sarcoplasmic reticulum lumen . Retained in the endoplasmic reticulum (ER), and sarcoplasmic reticulum (SR) under normal conditions (PubMed:22637475). Up-regulated and secreted by the ER/SR in response to ER stress and hypoxia (PubMed:22637475, PubMed:29497057). .
ExpressionTestis,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human MANF. AA range:11-60
Gene NameMANF
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgroundmesencephalic astrocyte derived neurotrophic factor(MANF) Homo sapiens The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. [provided by RefSeq, Apr 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-75309-Conjugate. Price: $485 / Size: 100μl.
E20-75309-FITC$485 / 100μlE20-75309-Biotin$485 / 100μlE20-75309-HRP$485 / 100μlE20-75309-AP$485 / 100μlE20-75309-AF350$485 / 100μlE20-75309-AF405M$485 / 100μlE20-75309-AF488$485 / 100μlE20-75309-AF514$485 / 100μlE20-75309-AF532$485 / 100μlE20-75309-AF555$485 / 100μlE20-75309-AF568$485 / 100μlE20-75309-AF405S$485 / 100μlE20-75309-AF405L$485 / 100μlE20-75309-AF546$485 / 100μlE20-75309-AF594$485 / 100μlE20-75309-AF610$485 / 100μlE20-75309-AF635$485 / 100μlE20-75309-AF647$485 / 100μlE20-75309-AF680$485 / 100μlE20-75309-AF700$485 / 100μlE20-75309-AF750$485 / 100μlE20-75309-AF790$485 / 100μlE20-75309-APC$485 / 100μlE20-75309-PE$485 / 100μlE20-75309-Cy3$485 / 100μlE20-75309-Cy5$485 / 100μlE20-75309-Cy5.5$485 / 100μlE20-75309-Cy7$485 / 100μlE20-75309-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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