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Cell Signal Transduction Research Antibodies
BMP-3A Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight53406Da
Protein NameBone morphogenetic protein 3
Human Gene Id651
Human Swiss Prot NoP12645
Mouse Gene Id110075
Mouse Swiss Prot NoQ8BHE5
Rat Gene Id25667
Rat Swiss Prot NoP49002
SpecificityBMP-3A Polyclonal Antibody detects endogenous levels of BMP-3A protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameBMP3; BMP3A; Bone morphogenetic protein 3; BMP-3; Bone morphogenetic protein 3A; BMP-3A; Osteogenin
Observed Band(KD)53
Functionfunction:Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.,induction:Highly expressed in fracture tissue, particularly in osteoblasts, osteoclasts and chondroblasts.,online information:Bone morphogenetic protein 3 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed in adult and fetal cartilage.,
Subcellular LocationSecreted.
ExpressionExpressed in adult and fetal cartilage.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human BMP3. AA range:421-470
Gene NameBMP3
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgroundbone morphogenetic protein 3(BMP3) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016],
Conjugated Antibody
This product is also available conjugated. Format: E20-75303-Conjugate. Price: $485 / Size: 100μl.
E20-75303-FITC$485 / 100μlE20-75303-Biotin$485 / 100μlE20-75303-HRP$485 / 100μlE20-75303-AP$485 / 100μlE20-75303-AF350$485 / 100μlE20-75303-AF405M$485 / 100μlE20-75303-AF488$485 / 100μlE20-75303-AF514$485 / 100μlE20-75303-AF532$485 / 100μlE20-75303-AF555$485 / 100μlE20-75303-AF568$485 / 100μlE20-75303-AF405S$485 / 100μlE20-75303-AF405L$485 / 100μlE20-75303-AF546$485 / 100μlE20-75303-AF594$485 / 100μlE20-75303-AF610$485 / 100μlE20-75303-AF635$485 / 100μlE20-75303-AF647$485 / 100μlE20-75303-AF680$485 / 100μlE20-75303-AF700$485 / 100μlE20-75303-AF750$485 / 100μlE20-75303-AF790$485 / 100μlE20-75303-APC$485 / 100μlE20-75303-PE$485 / 100μlE20-75303-Cy3$485 / 100μlE20-75303-Cy5$485 / 100μlE20-75303-Cy5.5$485 / 100μlE20-75303-Cy7$485 / 100μlE20-75303-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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