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Cell Signal Transduction Research Antibodies
VEGF-C Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight46883Da
Protein NameVascular endothelial growth factor C
Human Gene Id7424
Human Swiss Prot NoP49767
Mouse Gene Id22341
Mouse Swiss Prot NoP97953
Rat Gene Id114111
Rat Swiss Prot NoO35757
SpecificityVEGF-C Polyclonal Antibody detects endogenous levels of VEGF-C protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameVEGFC; Vascular endothelial growth factor C; VEGF-C; Flt4 ligand; Flt4-L; Vascular endothelial growth factor-related protein; VRP
Observed Band(KD)42
Functionfunction:Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors.,PTM:Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3, but only the fully processed form could activate VEGFR-2. VEGF-C first form an antiparallel homodimer linked by disulfide bonds. Before secretion, a cleavage occurs between Arg-227 and Ser-228 producing an heterotetramer. The next extracellular step of the processing removes the N-terminal propeptide. Finally the mature VEGF-C is compos
Subcellular LocationSecreted.
ExpressionSpleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human VEGFC. AA range:91-140
Gene NameVEGFC
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgroundvascular endothelial growth factor C(VEGFC) Homo sapiens The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-75297-Conjugate. Price: $485 / Size: 100μl.
E20-75297-FITC$485 / 100μlE20-75297-Biotin$485 / 100μlE20-75297-HRP$485 / 100μlE20-75297-AP$485 / 100μlE20-75297-AF350$485 / 100μlE20-75297-AF405M$485 / 100μlE20-75297-AF488$485 / 100μlE20-75297-AF514$485 / 100μlE20-75297-AF532$485 / 100μlE20-75297-AF555$485 / 100μlE20-75297-AF568$485 / 100μlE20-75297-AF405S$485 / 100μlE20-75297-AF405L$485 / 100μlE20-75297-AF546$485 / 100μlE20-75297-AF594$485 / 100μlE20-75297-AF610$485 / 100μlE20-75297-AF635$485 / 100μlE20-75297-AF647$485 / 100μlE20-75297-AF680$485 / 100μlE20-75297-AF700$485 / 100μlE20-75297-AF750$485 / 100μlE20-75297-AF790$485 / 100μlE20-75297-APC$485 / 100μlE20-75297-PE$485 / 100μlE20-75297-Cy3$485 / 100μlE20-75297-Cy5$485 / 100μlE20-75297-Cy5.5$485 / 100μlE20-75297-Cy7$485 / 100μlE20-75297-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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