CKR-3 Polyclonal Antibody

Name: CKR-3 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75289
Price: 225 USD
Availability: InStock

E20-75289Cite ID: EN0055422Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight41044Da

Protein NameC-C chemokine receptor type 3

Human Gene Id1232

Human Swiss Prot NoP51677

Mouse Gene Id12771

Mouse Swiss Prot NoP51678

Rat Gene Id117027

Rat Swiss Prot NoO54814

SpecificityCKR-3 Polyclonal Antibody detects endogenous levels of CKR-3 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameCCR3; CMKBR3; C-C chemokine receptor type 3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3; Eosinophil eotaxin receptor; CD193

Observed Band(KD)41

Functionfunction:Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.,online information:CC chemokine receptors entry,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Binds to HIV-1 Tat.,tissue specificity:In eosinophils as well as trace amounts in neutrophils and monocytes.,

Subcellular LocationCell membrane; Multi-pass membrane protein .

ExpressionIn eosinophils as well as trace amounts in neutrophils and monocytes.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human CCR3. AA range:1-50

Gene NameCCR3

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

BackgroundC-C motif chemokine receptor 3(CCR3) Homo sapiens The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75289-Conjugate. Price: $485 / Size: 100μl.

E20-75289-FITC$485 / 100μlE20-75289-Biotin$485 / 100μlE20-75289-HRP$485 / 100μlE20-75289-AP$485 / 100μlE20-75289-AF350$485 / 100μlE20-75289-AF405M$485 / 100μlE20-75289-AF488$485 / 100μlE20-75289-AF514$485 / 100μlE20-75289-AF532$485 / 100μlE20-75289-AF555$485 / 100μlE20-75289-AF568$485 / 100μlE20-75289-AF405S$485 / 100μlE20-75289-AF405L$485 / 100μlE20-75289-AF546$485 / 100μlE20-75289-AF594$485 / 100μlE20-75289-AF610$485 / 100μlE20-75289-AF635$485 / 100μlE20-75289-AF647$485 / 100μlE20-75289-AF680$485 / 100μlE20-75289-AF700$485 / 100μlE20-75289-AF750$485 / 100μlE20-75289-AF790$485 / 100μlE20-75289-APC$485 / 100μlE20-75289-PE$485 / 100μlE20-75289-Cy3$485 / 100μlE20-75289-Cy5$485 / 100μlE20-75289-Cy5.5$485 / 100μlE20-75289-Cy7$485 / 100μlE20-75289-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.