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Cell Signal Transduction Research Antibodies
CD160 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight19810Da
Protein NameCD160 antigen
Human Gene Id11126
Human Swiss Prot NoO95971
Mouse Gene Id54215
Mouse Swiss Prot NoO88875
SpecificityCD160 Polyclonal Antibody detects endogenous levels of CD160 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD160; BY55; CD160 antigen; Natural killer cell receptor BY55; CD160
Observed Band(KD)20
Functionfunction:Receptor showing broad specificity for both classical and non-classical MHC class I molecules.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Homomultimer; disulfide-linked.,tissue specificity:Expressed in spleen, peripheral blood, and small intestine. Expression is restricted to functional NK and T cytotoxic lymphocytes.,
Subcellular Location[CD160 antigen]: Cell membrane ; Lipid-anchor, GPI-anchor .; [CD160 antigen, soluble form]: Secreted. Released from the cell membrane by GPI cleavage. .
ExpressionExpression is restricted to functional NK and cytotoxic T lymphocytes. Expressed in viral-specific effector memory and terminally differentiated effector memory CD8+ T cells. Expressed in memory and activated CD4+ T cell subsets (at protein level) (PubMed:9743336, PubMed:18193050, PubMed:11978774, PubMed:25255144). Expressed at high levels in intraepithelial lymphocytes (at protein level) (PubMed:9743336). Expressed in both alpha-beta and gamma-delta CD8+ T cell subsets (at protein level) (PubMed:9743336, PubMed:18193050, PubMed:11978774). Expressed in umbilical vein endothelial cells (at protein level) (PubMed:16809620). Expressed in monocytes and at lower levels in B cells (PubMed:23761635). Isoform 3: Expressed exclusively in activated NK cells (at protein level) (PubMed:19109136).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD160. AA range:21-70
Gene NameCD160
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
BackgroundCD160 molecule(CD160) Homo sapiens CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. C
Conjugated Antibody
This product is also available conjugated. Format: E20-75286-Conjugate. Price: $485 / Size: 100μl.
E20-75286-FITC$485 / 100μlE20-75286-Biotin$485 / 100μlE20-75286-HRP$485 / 100μlE20-75286-AP$485 / 100μlE20-75286-AF350$485 / 100μlE20-75286-AF405M$485 / 100μlE20-75286-AF488$485 / 100μlE20-75286-AF514$485 / 100μlE20-75286-AF532$485 / 100μlE20-75286-AF555$485 / 100μlE20-75286-AF568$485 / 100μlE20-75286-AF405S$485 / 100μlE20-75286-AF405L$485 / 100μlE20-75286-AF546$485 / 100μlE20-75286-AF594$485 / 100μlE20-75286-AF610$485 / 100μlE20-75286-AF635$485 / 100μlE20-75286-AF647$485 / 100μlE20-75286-AF680$485 / 100μlE20-75286-AF700$485 / 100μlE20-75286-AF750$485 / 100μlE20-75286-AF790$485 / 100μlE20-75286-APC$485 / 100μlE20-75286-PE$485 / 100μlE20-75286-Cy3$485 / 100μlE20-75286-Cy5$485 / 100μlE20-75286-Cy5.5$485 / 100μlE20-75286-Cy7$485 / 100μlE20-75286-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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