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Cell Signal Transduction Research Antibodies
CD207 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight36725Da
Protein NameC-type lectin domain family 4 member K
Human Gene Id50489
Human Swiss Prot NoQ9UJ71
Mouse Gene Id246278
Mouse Swiss Prot NoQ8VBX4
SpecificityCD207 Polyclonal Antibody detects endogenous levels of CD207 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207
Observed Band(KD)38
Functionfunction:Calcium-dependent lectin displaying mannose-binding specificity, Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering.,online information:Langerin,similarity:Contains 1 C-type lectin domain.,subcellular location:Found in Birbeck granules (BGs), which are organelles consisting of superimposed and zippered membranes.,tissue specificity:Exclusively expressed by Langerhans cells.,
Subcellular LocationMembrane ; Single-pass type II membrane protein . Found in Birbeck granules (BGs), which are organelles consisting of superimposed and zippered membranes.
ExpressionExclusively expressed by Langerhans cells. Expressed in astrocytoma and malignant ependymoma, but not in normal brain tissues.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD207. AA range:61-110
Gene NameCD207
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundCD207 molecule(CD207) Homo sapiens The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010],
Conjugated Antibody
This product is also available conjugated. Format: E20-75275-Conjugate. Price: $485 / Size: 100μl.
E20-75275-FITC$485 / 100μlE20-75275-Biotin$485 / 100μlE20-75275-HRP$485 / 100μlE20-75275-AP$485 / 100μlE20-75275-AF350$485 / 100μlE20-75275-AF405M$485 / 100μlE20-75275-AF488$485 / 100μlE20-75275-AF514$485 / 100μlE20-75275-AF532$485 / 100μlE20-75275-AF555$485 / 100μlE20-75275-AF568$485 / 100μlE20-75275-AF405S$485 / 100μlE20-75275-AF405L$485 / 100μlE20-75275-AF546$485 / 100μlE20-75275-AF594$485 / 100μlE20-75275-AF610$485 / 100μlE20-75275-AF635$485 / 100μlE20-75275-AF647$485 / 100μlE20-75275-AF680$485 / 100μlE20-75275-AF700$485 / 100μlE20-75275-AF750$485 / 100μlE20-75275-AF790$485 / 100μlE20-75275-APC$485 / 100μlE20-75275-PE$485 / 100μlE20-75275-Cy3$485 / 100μlE20-75275-Cy5$485 / 100μlE20-75275-Cy5.5$485 / 100μlE20-75275-Cy7$485 / 100μlE20-75275-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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